iPTMnet Report for O75319 (DUSP11)


Protein Information

Cytoscape View


UniProt AC / UniProt ID O75319 / DUS11_HUMAN
Protein Name RNA/RNP complex-1-interacting phosphatase
Gene Name Name: DUSP11
Synonyms:PIR1;
Organism Homo sapiens (Human)

PRO ID PR:O75319
DAG View
PRO Name RNA/RNP complex-1-interacting phosphatase (human)
Definition An RNA/RNP complex-1-interacting phosphatase that is encoded in the genome of human.
Short Label hDUSP11
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


O75319 (DUSP11) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
R55 Methylation PhosphoSitePlus
K83 Ubiquitination PhosphoSitePlus
K101 Sumoylation PhosphoSitePlus
K101 Ubiquitination PhosphoSitePlus
K106 Ubiquitination PhosphoSitePlus
K111 Sumoylation PhosphoSitePlus
K111 Ubiquitination PhosphoSitePlus
K126 Ubiquitination PhosphoSitePlus
K148 Sumoylation PhosphoSitePlus
K176 Sumoylation PhosphoSitePlus
K176 Ubiquitination PhosphoSitePlus
K178 Sumoylation PhosphoSitePlus
K178 Ubiquitination PhosphoSitePlus
K186 Sumoylation PhosphoSitePlus
K186 Ubiquitination PhosphoSitePlus
C199 Methylation IEDB 31844290
K253 Ubiquitination PhosphoSitePlus
K281 Ubiquitination PhosphoSitePlus
R298 Methylation PhosphoSitePlus
R312 Methylation PhosphoSitePlus
K313 Methylation PhosphoSitePlus
K313 Sumoylation PhosphoSitePlus
K313 Ubiquitination PhosphoSitePlus
Y321 Phosphorylation PhosphoSitePlus
Y336 Phosphorylation PhosphoSitePlus
S337 Phosphorylation PhosphoSitePlus
Y341 Phosphorylation PhosphoSitePlus
S342 Phosphorylation PhosphoSitePlus
K346 Sumoylation PhosphoSitePlus
K346 Ubiquitination PhosphoSitePlus
R351 Methylation PhosphoSitePlus
Y360 Phosphorylation PhosphoSitePlus
C372 Methylation IEDB 31844290


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
R55 S55 Biomuta DOID:8618 / oral cavity cancer [ cosmic ]
K126 N126 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
K253 N253 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
R298 Q298 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ] DOID:4159 / skin cancer [ cosmic ] DOID:1324 / lung cancer [ cosmic ] DOID:9256 / colorectal cancer [ cosmic, icgc ]
R312 K312 Biomuta DOID:1324 / lung cancer [ cosmic ]
K313 T313 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S342 P342 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]