iPTMnet Report for O75190 (DNAJB6)


Protein Information

Cytoscape View


UniProt AC / UniProt ID O75190 / DNJB6_HUMAN
Protein Name DnaJ homolog subfamily B member 6
Gene Name Name: DNAJB6
Synonyms:HSJ2,MRJ,MSJ1;
Organism Homo sapiens (Human)

PRO ID PR:O75190
DAG View
PRO Name DnaJ homolog subfamily B member 6 (human)
Definition A DnaJ homolog subfamily B member 6 that is encoded in the genome of human.
Short Label hDNAJB6
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


O75190 (DNAJB6) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
Y4 Phosphorylation PhosphoSitePlus
S15 Phosphorylation PhosphoSitePlus
K20 Ubiquitination PhosphoSitePlus
K29 Ubiquitination PhosphoSitePlus
K34 Ubiquitination PhosphoSitePlus
K39 Ubiquitination PhosphoSitePlus
K47 Ubiquitination PhosphoSitePlus
Y53 Phosphorylation PhosphoSitePlus
S57 Phosphorylation PhosphoSitePlus
K60 Ubiquitination PhosphoSitePlus
K61 Ubiquitination PhosphoSitePlus
Y65 Phosphorylation PhosphoSitePlus
K67 Ubiquitination PhosphoSitePlus
R135 Methylation PhosphoSitePlus
K196 Ubiquitination PhosphoSitePlus
S226 Phosphorylation PhosphoSitePlus
T228 Phosphorylation PhosphoSitePlus
S267 Phosphorylation PhosphoSitePlus
S277 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163, 21406692, ...17081983
K302 Acetylation PhosphoSitePlus
K302 Ubiquitination PhosphoSitePlus
K306 Acetylation PhosphoSitePlus
K306 Ubiquitination PhosphoSitePlus
S316 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S277 Phosphorylation HPRD 17322306, 19413330, 18669648, ...20068231
Site PTM Type PTM Enzyme Score Source PMID
K225 Ubiquitination PhosphoSitePlus
K232 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S312 Phosphorylation PhosphoSitePlus
S315 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S15 * Biomuta DOID:4159 / skin cancer [ cosmic ]
K20 Q20 Biomuta DOID:8618 / oral cavity cancer [ cosmic ]
R135 * Biomuta DOID:4159 / skin cancer [ cosmic ]
R135 Q135 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ] DOID:9256 / colorectal cancer [ icgc ]
K232 M232 Biomuta DOID:2394 / ovarian cancer [ cosmic, icgc ]