Protein Information

Cytoscape View


UniProt AC / UniProt ID O75182 / SIN3B_HUMAN
Protein Name Paired amphipathic helix protein Sin3b
Gene Name Name: SIN3B
Synonyms:KIAA0700;
Organism Homo sapiens (Human)

PRO ID PR:O75182
DAG View
PRO Name paired amphipathic helix protein Sin3b (human)
Definition A paired amphipathic helix protein Sin3b that is encoded in the genome of human.
Short Label hSIN3B
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


O75182 (SIN3B) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S11 Phosphorylation PhosphoSitePlus
R19 Methylation PhosphoSitePlus
K36 Ubiquitination PhosphoSitePlus
S122 Phosphorylation PhosphoSitePlus
T125 Phosphorylation PhosphoSitePlus
Y146 Phosphorylation PhosphoSitePlus
K239 Ubiquitination PhosphoSitePlus
S241 Phosphorylation PhosphoSitePlus
T262 Phosphorylation PhosphoSitePlus
S266 Phosphorylation PhosphoSitePlus
S270 Phosphorylation PhosphoSitePlus
S273 Phosphorylation PhosphoSitePlus
S279 Phosphorylation PhosphoSitePlus
K284 Acetylation PhosphoSitePlus
T304 Phosphorylation PhosphoSitePlus
K406 Ubiquitination PhosphoSitePlus
K551 Ubiquitination PhosphoSitePlus
K590 Ubiquitination PhosphoSitePlus
K602 Ubiquitination PhosphoSitePlus
S719 Phosphorylation PhosphoSitePlus
S728 Phosphorylation PhosphoSitePlus
S739 Phosphorylation PhosphoSitePlus
S740 Phosphorylation PhosphoSitePlus
K817 Ubiquitination PhosphoSitePlus
T877 Phosphorylation PhosphoSitePlus
Y881 Phosphorylation PhosphoSitePlus
S1001 Phosphorylation PhosphoSitePlus
S1002 Phosphorylation phospho.ELM 18669648
S1003 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S1071 Phosphorylation PhosphoSitePlus
Y1074 Phosphorylation PhosphoSitePlus
Y1076 Phosphorylation PhosphoSitePlus
Y1151 Phosphorylation PhosphoSitePlus
Y1155 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S122 Phosphorylation HPRD 20068231
Y600 Phosphorylation HPRD 20068231
S1002 Phosphorylation HPRD 18669648
S1003 Phosphorylation HPRD 18669648, 20068231
Site PTM Type PTM Enzyme Score Source PMID
K444 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S122 P122 Biomuta DOID:1909 / melanoma [ cosmic ]
Y146 C146 Biomuta DOID:363 / uterine cancer [ tcga ]
S241 F241 Biomuta DOID:1909 / melanoma [ icgc, tcga ]
T262 I262 Biomuta DOID:1909 / melanoma [ tcga ]
S266 G266 Biomuta DOID:1324 / lung cancer [ tcga ]
S279 Y279 Biomuta DOID:1793 / pancreatic cancer [ icgc ] DOID:0070003 / blastoma [ cosmic ]
K817 N817 Biomuta DOID:3571 / liver cancer [ icgc ]
T877 P877 Biomuta DOID:9256 / colorectal cancer [ tcga ]
S1003 L1003 Biomuta DOID:363 / uterine cancer [ tcga ]
S1003 W1003 Biomuta DOID:2596 / larynx cancer [ cosmic ]
S1071 P1071 Biomuta DOID:4362 / cervical cancer [ cosmic ]
Y1074 F1074 Biomuta DOID:3070 / malignant glioma [ cosmic ]