Protein Information

Cytoscape View


UniProt AC / UniProt ID O75173 / ATS4_HUMAN
Protein Name A disintegrin and metalloproteinase with thrombospondin motifs 4 precursor
Gene Name Name: ADAMTS4
Synonyms:KIAA0688;ORFNames:UNQ769/PRO1563;
Organism Homo sapiens (Human)

PRO ID PR:O75173
DAG View
PRO Name a disintegrin and metalloproteinase with thrombospondin motifs 4 (human)
Definition An a disintegrin and metalloproteinase with thrombospondin motifs 4 that is encoded in the genome of human.
Short Label hADAMTS4
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


O75173 (ADAMTS4) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S53 Phosphorylation PhosphoSitePlus
N68 N-Glycosylation GlyGen 23090970, 24190977
S185 Phosphorylation PhosphoSitePlus
Y241 Phosphorylation PhosphoSitePlus
T244 Phosphorylation PhosphoSitePlus
T782 Phosphorylation IEDB 32387766
T813 O-Glycosylation GlyGen 30459171


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S185 R185 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]