iPTMnet Report for O75159 (SOCS5)


Protein Information

Cytoscape View


UniProt AC / UniProt ID O75159 / SOCS5_HUMAN
Protein Name Suppressor of cytokine signaling 5
Gene Name Name: SOCS5
Synonyms:CIS6,CISH5,CISH6,KIAA0671;
Organism Homo sapiens (Human)

PRO ID PR:O75159
DAG View
PRO Name suppressor of cytokine signaling 5 (human)
Definition A suppressor of cytokine signaling 5 that is encoded in the genome of human.
Short Label hSOCS5
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


O75159 (SOCS5) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K43 Ubiquitination PhosphoSitePlus
T51 Phosphorylation PhosphoSitePlus
S56 Phosphorylation PhosphoSitePlus
S57 Phosphorylation PhosphoSitePlus
Y156 Phosphorylation PhosphoSitePlus
S159 Phosphorylation PhosphoSitePlus
S160 Phosphorylation PhosphoSitePlus
T171 Phosphorylation PhosphoSitePlus
S174 Phosphorylation PhosphoSitePlus
S211 Phosphorylation PhosphoSitePlus
S344 Phosphorylation PhosphoSitePlus
C368 Methylation IEDB 31844290
S438 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K43 R43 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
S160 C160 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ] DOID:1324 / lung cancer [ cosmic ]