iPTMnet Report for O75155 (CAND2)


Protein Information

Cytoscape View


UniProt AC / UniProt ID O75155 / CAND2_HUMAN
Protein Name Cullin-associated NEDD8-dissociated protein 2
Gene Name Name: CAND2
Synonyms:KIAA0667,TIP120B;
Organism Homo sapiens (Human)

PRO ID PR:O75155
DAG View
PRO Name cullin-associated NEDD8-dissociated protein 2 (human)
Definition A cullin-associated NEDD8-dissociated protein 2 that is encoded in the genome of human.
Short Label hCAND2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


O75155 (CAND2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K20 Ubiquitination PhosphoSitePlus
K60 Acetylation PhosphoSitePlus
K60 Ubiquitination PhosphoSitePlus
K99 Ubiquitination PhosphoSitePlus
T122 Phosphorylation PhosphoSitePlus
S124 Phosphorylation PhosphoSitePlus
T128 Phosphorylation PhosphoSitePlus
S230 Phosphorylation PhosphoSitePlus
S318 Phosphorylation PhosphoSitePlus
S333 Phosphorylation PhosphoSitePlus
S337 Phosphorylation PhosphoSitePlus
Y341 Phosphorylation PhosphoSitePlus
S342 Phosphorylation PhosphoSitePlus
S365 Phosphorylation PhosphoSitePlus
T407 Phosphorylation PhosphoSitePlus
T581 Phosphorylation PhosphoSitePlus
K588 Ubiquitination PhosphoSitePlus
T635 Phosphorylation PhosphoSitePlus
S640 Phosphorylation PhosphoSitePlus
S659 Phosphorylation PhosphoSitePlus
S874 Phosphorylation PhosphoSitePlus
S929 O-Glycosylation GlyGen 29351928
R1087 Methylation PhosphoSitePlus
K1088 Methylation PhosphoSitePlus
S1224 Phosphorylation PhosphoSitePlus
S1226 Phosphorylation PhosphoSitePlus
S1229 Phosphorylation PhosphoSitePlus
T1230 Phosphorylation PhosphoSitePlus
S1236 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
K20 Ubiquitination PhosphoSitePlus
K60 Ubiquitination PhosphoSitePlus
S82 Phosphorylation PhosphoSitePlus
T136 Phosphorylation HPRD   PhosphoSitePlus 19664995
K1056 Acetylation PhosphoSitePlus
K1056 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S318 I318 Biomuta DOID:363 / uterine cancer [ icgc ]
S365 L365 Biomuta DOID:363 / uterine cancer [ icgc ] DOID:4159 / skin cancer [ cosmic ] DOID:9256 / colorectal cancer [ cosmic ]
S659 T659 Biomuta DOID:3571 / liver cancer [ cosmic ]
S659 L659 Biomuta [ cosmic ]
R1087 Q1087 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ] DOID:8618 / oral cavity cancer [ cosmic ]
R1087 W1087 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S1236 R1236 Biomuta DOID:8618 / oral cavity cancer [ cosmic ]