iPTMnet Report for O75153 (CLUH)


Protein Information

Cytoscape View


UniProt AC / UniProt ID O75153 / CLU_HUMAN
Protein Name Clustered mitochondria protein homolog
Gene Name Name: CLUH
Synonyms:KIAA0664;
Organism Homo sapiens (Human)

PRO ID PR:O75153
DAG View
PRO Name clustered mitochondria protein homolog (human)
Definition A clustered mitochondria protein homolog that is encoded in the genome of human.
Short Label hCLUH
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


O75153 (CLUH) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K175 Ubiquitination PhosphoSitePlus
K210 Ubiquitination PhosphoSitePlus
T255 Phosphorylation HPRD 20068231
S279 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 18669648
S281 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 18669648
K294 Acetylation PhosphoSitePlus
K295 Ubiquitination PhosphoSitePlus
K302 Ubiquitination PhosphoSitePlus
Y320 Phosphorylation PhosphoSitePlus
S321 Phosphorylation PhosphoSitePlus
T323 Phosphorylation PhosphoSitePlus
C333 Methylation IEDB 31844290
Y346 Phosphorylation PhosphoSitePlus
K384 Methylation PhosphoSitePlus
T394 Phosphorylation PhosphoSitePlus
S411 Phosphorylation HPRD   PhosphoSitePlus 20068231
K437 Ubiquitination PhosphoSitePlus
K529 Ubiquitination PhosphoSitePlus
K552 Ubiquitination PhosphoSitePlus
S654 Phosphorylation PhosphoSitePlus   UniProt 19690332
S664 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 19413330, 21406692, 15302935, ...18669648, 24275569, 20166139, 19690332, 20068231
S669 Phosphorylation PhosphoSitePlus
K676 Ubiquitination PhosphoSitePlus
K678 Ubiquitination PhosphoSitePlus
K703 Ubiquitination PhosphoSitePlus
S723 Phosphorylation PhosphoSitePlus   UniProt 23186163
K740 Ubiquitination PhosphoSitePlus
C753 S-Nitrosylation dbSNO 19483679
T818 Phosphorylation PhosphoSitePlus
Y946 Phosphorylation PhosphoSitePlus
S947 Phosphorylation PhosphoSitePlus
S950 Phosphorylation PhosphoSitePlus
K953 Ubiquitination PhosphoSitePlus
K969 Ubiquitination PhosphoSitePlus
K974 Ubiquitination PhosphoSitePlus
K988 Ubiquitination PhosphoSitePlus
C998 Methylation IEDB 31844290
K1159 Ubiquitination PhosphoSitePlus
K1170 Ubiquitination PhosphoSitePlus
K1177 Ubiquitination PhosphoSitePlus
K1186 Ubiquitination PhosphoSitePlus
T1187 Phosphorylation PhosphoSitePlus
K1195 Ubiquitination PhosphoSitePlus
Y1212 Phosphorylation PhosphoSitePlus
S1216 Phosphorylation PhosphoSitePlus
K1257 Ubiquitination PhosphoSitePlus
S1295 Phosphorylation PhosphoSitePlus
S1304 Phosphorylation PhosphoSitePlus
S1306 Phosphorylation HPRD   phospho.ELM 18669648


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S281 F281 Biomuta DOID:4159 / skin cancer [ cosmic ]
S669 N669 Biomuta DOID:1793 / pancreatic cancer [ icgc ]
S723 L723 Biomuta DOID:1612 / breast cancer [ cosmic ]
K1159 T1159 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
K1170 N1170 Biomuta DOID:4159 / skin cancer [ cosmic ]
K1170 R1170 Biomuta DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ]
T1187 N1187 Biomuta DOID:3571 / liver cancer [ cosmic ]
K1257 N1257 Biomuta DOID:5041 / esophageal cancer [ cosmic ]
S1295 F1295 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ] DOID:11054 / urinary bladder cancer [ cosmic, icgc ]