iPTMnet Report for O75146 (HIP1R)


Protein Information

Cytoscape View


UniProt AC / UniProt ID O75146 / HIP1R_HUMAN
Protein Name Huntingtin-interacting protein 1-related protein
Gene Name Name: HIP1R
Synonyms:HIP12,KIAA0655;
Organism Homo sapiens (Human)

PRO ID PR:O75146
DAG View
PRO Name huntingtin-interacting protein 1-related protein (human)
Definition A huntingtin-interacting protein 1-related protein that is encoded in the genome of human.
Short Label hHIP1R
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


O75146 (HIP1R) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
M1 Acetylation UniProt 22814378
S3 Phosphorylation PhosphoSitePlus
K5 Acetylation PhosphoSitePlus
K5 Ubiquitination PhosphoSitePlus
S13 Phosphorylation PhosphoSitePlus
S19 Phosphorylation PhosphoSitePlus
K29 Ubiquitination PhosphoSitePlus
K37 Ubiquitination PhosphoSitePlus
S80 Phosphorylation PhosphoSitePlus
S83 Phosphorylation PhosphoSitePlus
K146 Ubiquitination PhosphoSitePlus
S259 Phosphorylation PhosphoSitePlus
S293 Phosphorylation PhosphoSitePlus
K404 Ubiquitination PhosphoSitePlus
S541 Phosphorylation PhosphoSitePlus
S553 Phosphorylation PhosphoSitePlus
S560 Phosphorylation PhosphoSitePlus
S575 Phosphorylation PhosphoSitePlus
S640 Phosphorylation PhosphoSitePlus
T651 O-Glycosylation GlyGen 30459171
S652 O-Glycosylation GlyGen 30459171
C725 Methylation IEDB 31844290
T839 Phosphorylation PhosphoSitePlus
T840 Phosphorylation PhosphoSitePlus
T842 Phosphorylation PhosphoSitePlus
K864 Ubiquitination PhosphoSitePlus
S929 Phosphorylation PhosphoSitePlus
S1017 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648
S1045 Phosphorylation PhosphoSitePlus
Y1061 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S1015 Phosphorylation HPRD 20068231
S1017 Phosphorylation HPRD 18669648, 20068231


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K37 N37 Biomuta DOID:1612 / breast cancer [ cosmic ]
S553 N553 Biomuta DOID:363 / uterine cancer [ icgc ]
T839 M839 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S929 N929 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S1017 R1017 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]