iPTMnet Report for O75145 (PPFIA3)
Protein Information
| UniProt AC / UniProt ID | O75145 / LIPA3_HUMAN |
| Protein Name | Liprin-alpha-3 |
| Gene Name | Name: PPFIA3 Synonyms:KIAA0654; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:O75145 |
| PRO Name | liprin-alpha-3 (human) |
| Definition | A liprin-alpha-3 that is encoded in the genome of human. |
| Short Label | hPPFIA3 |
| Category | organism-gene |
O75145 (PPFIA3) as Substrate
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| S17 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus UniProt | 18669648, 23186163, 19690332 | ||
| T55 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S75 | Phosphorylation | score1 | PhosphoSitePlus | |||
| C122 | Methylation | score1 | IEDB | 31844290 | ||
| S130 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S142 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 | ||
| T195 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S207 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 19690332 | ||
| T220 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S231 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S264 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T272 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K292 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K387 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K450 | Ubiquitination | score1 | PhosphoSitePlus | |||
| Y505 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S508 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S512 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y533 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S537 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S645 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S683 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 | ||
| T689 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T714 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus UniProt | 18669648, 23186163, 19690332 | ||
| T718 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus | 18669648 | ||
| S721 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S765 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S766 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S786 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K807 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K821 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K866 | Ubiquitination | score1 | PhosphoSitePlus | |||
| T1033 | O-Glycosylation | score1 | GlyGen | 30379171, 28657654 | ||
| S1105 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T1112 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K1122 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S1123 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S1127 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S1129 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S1164 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 | ||
| K1171 | Ubiquitination | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| S264 | R264 | Biomuta | DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ] | |
| S264 | N264 | Biomuta | DOID:363 / uterine cancer [ icgc ] DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ] | |
| K450 | N450 | Biomuta | DOID:363 / uterine cancer [ icgc ] | |
| Y533 | C533 | Biomuta | DOID:10534 / stomach cancer [ cosmic, icgc ] | |
| S645 | L645 | Biomuta | DOID:363 / uterine cancer [ icgc ] | |
| T718 | N718 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] | |
| S765 | L765 | Biomuta | DOID:1612 / breast cancer [ icgc ] DOID:1324 / lung cancer [ cosmic ] | |
| K807 | Q807 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
| S1164 | F1164 | Biomuta | DOID:4159 / skin cancer [ cosmic ] DOID:8618 / oral cavity cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ] DOID:11054 / urinary bladder cancer [ cosmic ] | |
| S1164 | Y1164 | Biomuta | DOID:4159 / skin cancer [ cosmic ] |
DAG View