iPTMnet Report for O75143 (ATG13)


Protein Information

Cytoscape View


UniProt AC / UniProt ID O75143 / ATG13_HUMAN
Protein Name Autophagy-related protein 13
Gene Name Name: ATG13
Synonyms:KIAA0652;
Organism Homo sapiens (Human)

PRO ID PR:O75143
DAG View
PRO Name autophagy-related protein 13 (human)
Definition An autophagy-related protein 13 that is encoded in the genome of human.
Short Label hATG13
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


O75143 (ATG13) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
Phosphorylation PRO
M1 Acetylation UniProt 19413330, 22814378
S7 Phosphorylation PhosphoSitePlus
C38 Methylation IEDB 31844290
S44 Phosphorylation PhosphoSitePlus
K56 Ubiquitination PhosphoSitePlus
S114 O-Glycosylation GlyGen 30620550
S141 Phosphorylation PhosphoSitePlus
K143 Ubiquitination PhosphoSitePlus
T170 Phosphorylation PhosphoSitePlus
T204 Phosphorylation PhosphoSitePlus
S224 Phosphorylation PhosphoSitePlus
S259 Phosphorylation RLIMS-P 31733992
V318 Phosphorylation IntAct 24603492
T332 Phosphorylation PhosphoSitePlus
S334 Phosphorylation PhosphoSitePlus
T342 Phosphorylation PhosphoSitePlus
S355 Phosphorylation PhosphoSitePlus   UniProt 26138443, 23186163, 24275569, ...21855797
S355 Phosphorylation O75385 (ULK1) PhosphoSitePlus 26138443, 21855797
S356 Phosphorylation PhosphoSitePlus   UniProt 24275569
S361 Phosphorylation PhosphoSitePlus   UniProt 23186163
S389 Phosphorylation PhosphoSitePlus
K504 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S324 Phosphorylation HPRD 19651622


Proteoforms

PRO ID (Short Label) Sites PTM Enzyme Source PMID
PR:000046411 (hATG13/PhosRes+) p PRO


PTM-dependent PPI

PTM type Substrate Site Interactant Association type Source PMID
Phosphorylation Q8IYT8 (ULK2) S1027 O75143 (ATG13) increased_association eFIP 26052940


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S44 F44 Biomuta DOID:8618 / oral cavity cancer [ cosmic ]
S259 F259 Biomuta [ cosmic ] DOID:1115 / sarcoma [ icgc ]
T332 P332 Biomuta DOID:1612 / breast cancer [ cosmic ]
T332 S332 Biomuta DOID:1781 / thyroid gland cancer [ cosmic ]
S355 I355 Biomuta DOID:3571 / liver cancer [ cosmic ]
S389 G389 Biomuta DOID:1319 / brain cancer [ cosmic ]