iPTMnet Report for O75131 (CPNE3)


Protein Information

Cytoscape View


UniProt AC / UniProt ID O75131 / CPNE3_HUMAN
Protein Name Copine-3
Gene Name Name: CPNE3
Synonyms:CPN3,KIAA0636;
Organism Homo sapiens (Human)

PRO ID PR:O75131
DAG View
PRO Name copine-3 (human)
Definition A copine-3 that is encoded in the genome of human.
Short Label hCPNE3
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


O75131 (CPNE3) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S14 Phosphorylation PhosphoSitePlus   UniProt 23186163, 24275569
K21 Ubiquitination PhosphoSitePlus
S25 Phosphorylation PhosphoSitePlus
K52 Ubiquitination PhosphoSitePlus
C54 S-Nitrosylation dbSNO 22178444
S60 Phosphorylation PhosphoSitePlus
K61 Ubiquitination PhosphoSitePlus
K76 Ubiquitination PhosphoSitePlus
S90 Phosphorylation PhosphoSitePlus
K109 Ubiquitination PhosphoSitePlus
T119 O-Glycosylation GlyGen 23301498, 35008409, 33214551, ...35138101, 30379171, 34725712, 29351928, 34019948, 32870666, 32119511
K125 Ubiquitination PhosphoSitePlus
K136 Ubiquitination PhosphoSitePlus
K149 Ubiquitination PhosphoSitePlus
K153 Ubiquitination PhosphoSitePlus
K158 Ubiquitination PhosphoSitePlus
S159 Phosphorylation PhosphoSitePlus
K167 Acetylation PhosphoSitePlus
K167 Ubiquitination PhosphoSitePlus
K184 Ubiquitination PhosphoSitePlus
S197 Phosphorylation PhosphoSitePlus   UniProt 24275569
S200 Phosphorylation PhosphoSitePlus
Y203 Phosphorylation PhosphoSitePlus
K208 Ubiquitination PhosphoSitePlus
T209 Phosphorylation PhosphoSitePlus
K235 Ubiquitination PhosphoSitePlus
S240 Phosphorylation HPRD   PhosphoSitePlus 20068231
S242 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 18669648, 18452278
S243 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163
K253 Ubiquitination PhosphoSitePlus
K262 Ubiquitination PhosphoSitePlus
S268 Phosphorylation PhosphoSitePlus
K390 Ubiquitination PhosphoSitePlus
Y392 Phosphorylation PhosphoSitePlus
S476 Phosphorylation PhosphoSitePlus
K528 Ubiquitination PhosphoSitePlus
K533 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S14 F14 Biomuta DOID:4159 / skin cancer [ cosmic ]
S25 * Biomuta DOID:4159 / skin cancer [ cosmic ]
C54 S54 Biomuta DOID:1324 / lung cancer [ cosmic ]
C54 F54 Biomuta DOID:1324 / lung cancer [ cosmic ]
S60 F60 Biomuta DOID:4159 / skin cancer [ cosmic ]
K61 N61 Biomuta DOID:10534 / stomach cancer [ cosmic ]
S159 * Biomuta DOID:10283 / prostate cancer [ cosmic ]
S197 C197 Biomuta DOID:1793 / pancreatic cancer [ cosmic ]
S200 * Biomuta DOID:4362 / cervical cancer [ cosmic ]
K253 N253 Biomuta DOID:363 / uterine cancer [ cosmic ]
Y392 C392 Biomuta DOID:8618 / oral cavity cancer [ cosmic ]