iPTMnet Report for O75129 (ASTN2)


Protein Information

Cytoscape View


UniProt AC / UniProt ID O75129 / ASTN2_HUMAN
Protein Name Astrotactin-2 precursor
Gene Name Name: ASTN2
Synonyms:KIAA0634;
Organism Homo sapiens (Human)

PRO ID PR:O75129
DAG View
PRO Name astrotactin-2 (human)
Definition An astrotactin-2 that is encoded in the genome of human.
Short Label hASTN2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


O75129 (ASTN2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S245 Phosphorylation PhosphoSitePlus
S278 Phosphorylation PhosphoSitePlus
S388 Phosphorylation PhosphoSitePlus
S430 Phosphorylation PhosphoSitePlus
N493 N-Glycosylation GlyGen 24190977
K667 Acetylation PhosphoSitePlus
K686 Acetylation PhosphoSitePlus
S767 Phosphorylation PhosphoSitePlus
N770 N-Glycosylation GlyGen 24190977
N782 N-Glycosylation GlyGen 24190977
N783 N-Glycosylation GlyGen 24190977
K1023 Ubiquitination PhosphoSitePlus
Y1034 Phosphorylation PhosphoSitePlus
S1079 O-Glycosylation GlyGen 28314751
T1317 Phosphorylation IEDB 32387766
T1320 Phosphorylation IEDB   PhosphoSitePlus 32387766
S1327 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S1232 Phosphorylation HPRD 18691976
Site PTM Type PTM Enzyme Score Source PMID
S335 Phosphorylation HPRD 18691976


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S245 N245 Biomuta DOID:3953 / adrenal gland cancer [ cosmic ]
S278 F278 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S388 Y388 Biomuta DOID:363 / uterine cancer [ icgc ]
S388 C388 Biomuta DOID:8618 / oral cavity cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ]
S430 G430 Biomuta DOID:263 / kidney cancer [ cosmic ]
N782 H782 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
N782 D782 Biomuta DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ]
S1079 F1079 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
T1317 S1317 Biomuta DOID:5158 / pleural cancer [ cosmic ]
S1327 L1327 Biomuta DOID:363 / uterine cancer [ icgc ]