iPTMnet Report for O75096 (LRP4)
Protein Information
UniProt AC / UniProt ID | O75096 / LRP4_HUMAN |
Protein Name | Low-density lipoprotein receptor-related protein 4 precursor |
Gene Name | Name: LRP4 Synonyms:KIAA0816,LRP10,MEGF7; |
Organism | Homo sapiens (Human) |
PRO ID | PR:O75096 |
PRO Name | low-density lipoprotein receptor-related protein 4 (human) |
Definition | A low-density lipoprotein receptor-related protein 4 that is encoded in the genome of human. |
Short Label | hLRP4 |
Category | organism-gene |
O75096 (LRP4) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
T70 | O-Glycosylation | score1 | GlyGen | 30459171 | ||
S184 | O-Glycosylation | score1 | GlyGen | 30459171 | ||
T604 | O-Glycosylation | score1 | GlyGen | 29351928 | ||
T689 | Phosphorylation | score1 | PhosphoSitePlus | |||
S733 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y918 | Phosphorylation | score1 | PhosphoSitePlus | |||
S935 | Phosphorylation | score1 | PhosphoSitePlus | |||
T975 | Phosphorylation | score1 | PhosphoSitePlus | |||
S1113 | Phosphorylation | score1 | PhosphoSitePlus | |||
T1126 | Phosphorylation | score1 | PhosphoSitePlus | |||
N1415 | N-Glycosylation | score1 | GlyGen | 24190977 | ||
N1418 | N-Glycosylation | score1 | GlyGen | 24190977 | ||
N1467 | N-Glycosylation | score1 | GlyGen | 24190977 | ||
N1468 | N-Glycosylation | score1 | GlyGen | 24190977 | ||
Y1484 | Phosphorylation | score1 | PhosphoSitePlus | |||
T1512 | Phosphorylation | score1 | PhosphoSitePlus | |||
T1688 | O-Glycosylation | score2 | GlyGen PhosphoSitePlus | 23584533 | ||
S1689 | O-Glycosylation | score2 | GlyGen PhosphoSitePlus | 23584533 | ||
K1753 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y1764 | Phosphorylation | score1 | PhosphoSitePlus | |||
K1777 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y1787 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y1792 | Phosphorylation | score1 | PhosphoSitePlus | |||
R1833 | Methylation | score1 | PhosphoSitePlus | |||
S1887 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
T689 | I689 | Biomuta | DOID:4159 / skin cancer [ cosmic, icgc ] | |
T1126 | S1126 | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
N1468 | Y1468 | Biomuta | DOID:263 / kidney cancer [ cosmic ] | |
T1512 | I1512 | Biomuta | DOID:1612 / breast cancer [ cosmic ] | |
T1688 | M1688 | Biomuta | DOID:2531 / hematologic cancer [ cosmic ] | |
K1753 | R1753 | Biomuta | DOID:10534 / stomach cancer [ cosmic, icgc ] | |
R1833 | W1833 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] DOID:1324 / lung cancer [ cosmic, icgc ] |