iPTMnet Report for O75094 (SLIT3)


Protein Information

Cytoscape View


UniProt AC / UniProt ID O75094 / SLIT3_HUMAN
Protein Name Slit homolog 3 protein precursor
Gene Name Name: SLIT3
Synonyms:KIAA0814,MEGF5,SLIL2;ORFNames:UNQ691/PRO1336;
Organism Homo sapiens (Human)

PRO ID PR:O75094
DAG View
PRO Name slit homolog 3 protein (human)
Definition A slit homolog 3 protein that is encoded in the genome of human.
Short Label hSLIT3
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


O75094 (SLIT3) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T417 Phosphorylation PhosphoSitePlus
S419 Phosphorylation PhosphoSitePlus
K473 Acetylation PhosphoSitePlus
K561 Acetylation PhosphoSitePlus
S582 Phosphorylation PhosphoSitePlus
S605 Phosphorylation PhosphoSitePlus
T609 Phosphorylation PhosphoSitePlus
S1067 O-Glycosylation GlyGen 28657654
S1173 Phosphorylation PhosphoSitePlus
N1181 N-Glycosylation GlyGen 29741879
T1295 O-Glycosylation GlyGen   PhosphoSitePlus 23584533
T1385 Phosphorylation PhosphoSitePlus
T1387 Phosphorylation PhosphoSitePlus
S1388 Phosphorylation PhosphoSitePlus
Y1389 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S605 G605 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
T609 I609 Biomuta DOID:1793 / pancreatic cancer [ cosmic ] DOID:4159 / skin cancer [ cosmic ]
S1067 N1067 Biomuta DOID:4159 / skin cancer [ cosmic ]
S1173 Y1173 Biomuta DOID:1324 / lung cancer [ cosmic ]
S1388 L1388 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]