iPTMnet Report for O75093 (SLIT1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID O75093 / SLIT1_HUMAN
Protein Name Slit homolog 1 protein precursor
Gene Name Name: SLIT1
Synonyms:KIAA0813,MEGF4,SLIL1;
Organism Homo sapiens (Human)

PRO ID PR:O75093
DAG View
PRO Name slit homolog 1 protein (human)
Definition A slit homolog 1 protein that is encoded in the genome of human.
Short Label hSLIT1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


O75093 (SLIT1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
N72 N-Glycosylation GlyGen 24190977
T74 Phosphorylation PhosphoSitePlus
K78 Acetylation PhosphoSitePlus
K78 Ubiquitination PhosphoSitePlus
K85 Acetylation PhosphoSitePlus
K85 Ubiquitination PhosphoSitePlus
K109 Ubiquitination PhosphoSitePlus
K160 Ubiquitination PhosphoSitePlus
K166 Ubiquitination PhosphoSitePlus
N167 N-Glycosylation GlyGen 24190977
N189 N-Glycosylation GlyGen 24190977
N190 N-Glycosylation GlyGen 24190977
N191 N-Glycosylation GlyGen 24190977
N192 N-Glycosylation GlyGen 24190977
K298 Ubiquitination PhosphoSitePlus
Y332 Phosphorylation PhosphoSitePlus
K475 Acetylation PhosphoSitePlus
K516 Ubiquitination PhosphoSitePlus
K533 Ubiquitination PhosphoSitePlus
S553 Phosphorylation PhosphoSitePlus
T565 Phosphorylation PhosphoSitePlus
N623 N-Glycosylation GlyGen 24190977
N630 N-Glycosylation GlyGen 24190977
K690 Ubiquitination PhosphoSitePlus
K882 Ubiquitination PhosphoSitePlus
K911 Ubiquitination PhosphoSitePlus
N1306 N-Glycosylation GlyGen 24190977


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K78 N78 Biomuta DOID:363 / uterine cancer [ icgc ]
K109 R109 Biomuta DOID:1319 / brain cancer [ cosmic ]
K166 N166 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
N190 K190 Biomuta DOID:1324 / lung cancer [ cosmic ]
N623 K623 Biomuta DOID:8618 / oral cavity cancer [ cosmic ] DOID:1781 / thyroid gland cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ] DOID:1781 / thyroid cancer [ icgc ]
K882 E882 Biomuta DOID:9256 / colorectal cancer [ cosmic ]