Protein Information

Cytoscape View


UniProt AC / UniProt ID O75083 / WDR1_HUMAN
Protein Name WD repeat-containing protein 1
Gene Name Name: WDR1
Organism Homo sapiens (Human)

PRO ID PR:O75083
DAG View
PRO Name WD repeat-containing protein 1 (human)
Definition A WD repeat-containing protein 1 that is encoded in the genome of human.
Short Label hWDR1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


O75083 (WDR1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
Y3 Phosphorylation PhosphoSitePlus
K7 Ubiquitination PhosphoSitePlus
S11 Phosphorylation PhosphoSitePlus
R17 Methylation PhosphoSitePlus
S20 Phosphorylation PhosphoSitePlus
K21 Ubiquitination PhosphoSitePlus
K28 Acetylation PhosphoSitePlus   UniProt 19608861
K28 Ubiquitination PhosphoSitePlus
Y34 Phosphorylation PhosphoSitePlus
K38 Acetylation PhosphoSitePlus
K38 Ubiquitination PhosphoSitePlus
Y54 Phosphorylation PhosphoSitePlus
T55 Phosphorylation PhosphoSitePlus
K65 Ubiquitination PhosphoSitePlus
Y72 Phosphorylation PhosphoSitePlus
S75 Phosphorylation PhosphoSitePlus
S79 Phosphorylation PhosphoSitePlus
K81 Acetylation PhosphoSitePlus   UniProt 19608861
K81 Ubiquitination PhosphoSitePlus
R83 Methylation PhosphoSitePlus
K90 Ubiquitination PhosphoSitePlus
K95 Acetylation PhosphoSitePlus   UniProt 19608861
K95 Ubiquitination PhosphoSitePlus
Y96 Phosphorylation PhosphoSitePlus
Y98 Phosphorylation PhosphoSitePlus
K104 Acetylation PhosphoSitePlus
K104 Ubiquitination PhosphoSitePlus
K106 Ubiquitination PhosphoSitePlus
K115 Acetylation PhosphoSitePlus   UniProt 19608861
K115 Ubiquitination PhosphoSitePlus
K126 Ubiquitination PhosphoSitePlus
S151 Phosphorylation PhosphoSitePlus
K155 Ubiquitination PhosphoSitePlus
T164 Phosphorylation PhosphoSitePlus
S166 Phosphorylation PhosphoSitePlus
K180 Acetylation PhosphoSitePlus
K180 Ubiquitination PhosphoSitePlus
K182 Acetylation PhosphoSitePlus
K182 Ubiquitination PhosphoSitePlus
Y214 Phosphorylation PhosphoSitePlus
K219 Acetylation PhosphoSitePlus
K219 Ubiquitination PhosphoSitePlus
K223 Acetylation PhosphoSitePlus
K223 Ubiquitination PhosphoSitePlus
K231 Ubiquitination PhosphoSitePlus
Y238 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 15592455, 19690332
S241 Phosphorylation PhosphoSitePlus
K256 Acetylation PhosphoSitePlus
K256 Ubiquitination PhosphoSitePlus
Y300 Phosphorylation PhosphoSitePlus
S310 Phosphorylation PhosphoSitePlus
K311 Ubiquitination PhosphoSitePlus
K317 Ubiquitination PhosphoSitePlus
K321 Acetylation PhosphoSitePlus
K321 Ubiquitination PhosphoSitePlus
S322 Phosphorylation PhosphoSitePlus
T327 Phosphorylation PhosphoSitePlus
K330 Acetylation PhosphoSitePlus
K330 Ubiquitination PhosphoSitePlus
K334 Ubiquitination PhosphoSitePlus
Y348 Phosphorylation PhosphoSitePlus
S351 Phosphorylation PhosphoSitePlus
S358 Phosphorylation PhosphoSitePlus
K362 Ubiquitination PhosphoSitePlus
S383 Phosphorylation PhosphoSitePlus
S392 Phosphorylation PhosphoSitePlus
R396 Methylation PhosphoSitePlus
Y398 Phosphorylation PhosphoSitePlus
S399 Phosphorylation PhosphoSitePlus
K405 Ubiquitination PhosphoSitePlus
K437 Ubiquitination PhosphoSitePlus
Y472 Phosphorylation PhosphoSitePlus
S473 Phosphorylation PhosphoSitePlus
K480 Acetylation PhosphoSitePlus   UniProt 19608861
K480 Ubiquitination PhosphoSitePlus
K484 Ubiquitination PhosphoSitePlus
K489 Ubiquitination PhosphoSitePlus
K569 Acetylation PhosphoSitePlus
K569 Ubiquitination PhosphoSitePlus
S580 Phosphorylation PhosphoSitePlus
S581 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S20 Phosphorylation HPRD 20068231
Y238 Phosphorylation HPRD 15592455
Site PTM Type PTM Enzyme Score Source PMID
S20 Phosphorylation HPRD 20068231
Y98 Phosphorylation HPRD 15592455


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K21 N21 Biomuta DOID:0070003 / blastoma [ cosmic ]
Y96 C96 Biomuta DOID:1793 / pancreatic cancer [ tcga ]
K126 N126 Biomuta DOID:1324 / lung cancer [ cosmic ]
T164 M164 Biomuta DOID:363 / uterine cancer [ tcga ]
Y300 D300 Biomuta DOID:1324 / lung cancer [ cosmic, tcga ]
K317 E317 Biomuta DOID:363 / uterine cancer [ tcga ]
S322 L322 Biomuta DOID:1909 / melanoma [ icgc, tcga ]
S322 P322 Biomuta DOID:0070003 / blastoma [ cosmic ]
S358 F358 Biomuta DOID:1909 / melanoma [ icgc, tcga ]
R396 L396 Biomuta DOID:263 / kidney cancer [ tcga ]
R396 Q396 Biomuta DOID:10534 / stomach cancer [ cosmic ]
S399 I399 Biomuta DOID:363 / uterine cancer [ tcga ]
S399 G399 Biomuta DOID:10283 / prostate cancer [ cosmic ]
S399 C399 Biomuta DOID:1324 / lung cancer [ cosmic, tcga ]
S473 F473 Biomuta DOID:1909 / melanoma [ icgc ]