iPTMnet Report for O75069 (TMCC2)


Protein Information

Cytoscape View


UniProt AC / UniProt ID O75069 / TMCC2_HUMAN
Protein Name Transmembrane and coiled-coil domains protein 2
Gene Name Name: TMCC2
Synonyms:KIAA0481;ORFNames:hucep-11;
Organism Homo sapiens (Human)

PRO ID PR:O75069
DAG View
PRO Name transmembrane and coiled-coil domains protein 2 (human)
Definition A transmembrane and coiled-coil domains protein 2 that is encoded in the genome of human.
Short Label hTMCC2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


O75069 (TMCC2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T48 Phosphorylation PhosphoSitePlus
S49 Phosphorylation PhosphoSitePlus
S194 Phosphorylation PhosphoSitePlus
T226 Phosphorylation PhosphoSitePlus
S330 Phosphorylation PhosphoSitePlus
S438 Phosphorylation PhosphoSitePlus
K446 Acetylation PhosphoSitePlus
S462 Phosphorylation PhosphoSitePlus
S464 Phosphorylation PhosphoSitePlus   UniProt 23186163
T466 Phosphorylation PhosphoSitePlus
S469 Phosphorylation PhosphoSitePlus
T581 Phosphorylation PhosphoSitePlus
S589 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S330 Phosphorylation HPRD 19664994
S470 Phosphorylation HPRD 15345747


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T226 S226 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
S438 R438 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S469 F469 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
T581 M581 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]