iPTMnet Report for O75056 (SDC3)
Protein Information
| UniProt AC / UniProt ID | O75056 / SDC3_HUMAN |
| Protein Name | Syndecan-3 |
| Gene Name | Name: SDC3 Synonyms:KIAA0468; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:O75056 |
| PRO Name | syndecan-3 (human) |
| Definition | A syndecan-3 that is encoded in the genome of human. |
| Short Label | hSDC3 |
| Category | organism-gene |
DAG ViewO75056 (SDC3) as Substrate
 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| S108 | O-Glycosylation | score3 | GlyGen UniProt | 12407114 | ||
| T109 | O-Glycosylation | score3 | GlyGen UniProt | 12407114 | ||
| T110 | O-Glycosylation | score3 | GlyGen UniProt | 12407114 | ||
| T146 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S160 | O-Glycosylation | score3 | GlyGen UniProt | 12407114 | ||
| T161 | O-Glycosylation | score3 | GlyGen UniProt | 12407114 | ||
| T162 | O-Glycosylation | score3 | GlyGen UniProt | 12407114 | ||
| T169 | O-Glycosylation | score3 | GlyGen UniProt | 12407114 | ||
| S170 | O-Glycosylation | score3 | GlyGen UniProt | 12407114 | ||
| T171 | O-Glycosylation | score3 | GlyGen UniProt | 12407114 | ||
| T217 | O-Glycosylation | score1 | GlyGen | 25813380 | ||
| T218 | O-Glycosylation | score1 | GlyGen | 25813380 | ||
| T221 | O-Glycosylation | score1 | GlyGen | 25813380 | ||
| T225 | O-Glycosylation | score1 | GlyGen | 30459171 | ||
| T234 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T245 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S250 | O-Glycosylation | score2 | GlyGen PhosphoSitePlus | 23584533 | ||
| T251 | O-Glycosylation | score2 | GlyGen PhosphoSitePlus | 23584533 | ||
| T253 | O-Glycosylation | score2 | GlyGen PhosphoSitePlus | 23584533 | ||
| T264 | O-Glycosylation | score2 | GlyGen PhosphoSitePlus | 23584533, 30459171, 25813380 | ||
| T265 | O-Glycosylation | score2 | GlyGen PhosphoSitePlus | 23584533, 25813380 | ||
| T291 | O-Glycosylation | score1 | GlyGen | 25813380 | ||
| T293 | O-Glycosylation | score1 | GlyGen | 25813380 | ||
| T324 | O-Glycosylation | score1 | GlyGen | 30459171 | ||
| S344 | O-Glycosylation | score2 | GlyGen PhosphoSitePlus | 23584533, 25813380 | ||
| T349 | O-Glycosylation | score2 | GlyGen PhosphoSitePlus | 23584533 | ||
| T349 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y409 | Phosphorylation | score3 | HPRD phospho.ELM UniProt | 9388509 | ||
| Y409 | Phosphorylation | P54760 (EPHB4) | score1 | HPRD | 9388509 | |
| K414 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S418 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y419 | Phosphorylation | score3 | HPRD phospho.ELM UniProt | 9388509 | ||
| Y419 | Phosphorylation | P54760 (EPHB4) | score1 | HPRD | 9388509 | |
| S428 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y431 | Phosphorylation | score3 | HPRD phospho.ELM UniProt | 9388509 | ||
| Y431 | Phosphorylation | P54760 (EPHB4) | score1 | HPRD | 9388509 | |
| K433 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K436 | Ubiquitination | score1 | PhosphoSitePlus | |||
| Y441 | Phosphorylation | score3 | phospho.ELM PhosphoSitePlus UniProt | 9388509 |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| T169 | I169 | Biomuta | DOID:2531 / hematologic cancer [ cosmic ] | |
| T221 | K221 | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
| T221 | M221 | Biomuta | DOID:9256 / colorectal cancer [ cosmic, icgc ] DOID:9253 / gastrointestinal stromal tumor [ cosmic ] | |
| S250 | N250 | Biomuta | DOID:1319 / brain cancer [ icgc ] | |
| T293 | S293 | Biomuta | DOID:3571 / liver cancer [ cosmic ] | |
| S344 | L344 | Biomuta | DOID:1612 / breast cancer [ cosmic ] | |
| K414 | N414 | Biomuta | DOID:4159 / skin cancer [ cosmic, icgc ] | |
| K433 | T433 | Biomuta | DOID:10283 / prostate cancer [ cosmic, icgc ] | |
| K436 | R436 | Biomuta | DOID:1324 / lung cancer [ cosmic ] |
