iPTMnet Report for O75054 (IGSF3)


Protein Information

Cytoscape View


UniProt AC / UniProt ID O75054 / IGSF3_HUMAN
Protein Name Immunoglobulin superfamily member 3 precursor
Gene Name Name: IGSF3
Synonyms:EWI3,KIAA0466;
Organism Homo sapiens (Human)

PRO ID PR:O75054
DAG View
PRO Name immunoglobulin superfamily member 3 (human)
Definition An immunoglobulin superfamily member 3 that is encoded in the genome of human.
Short Label hIGSF3
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


O75054 (IGSF3) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
N101 N-Glycosylation GlyGen 23090970, 24190977
S199 Phosphorylation PhosphoSitePlus
T282 Phosphorylation PhosphoSitePlus
T293 Phosphorylation PhosphoSitePlus
Y374 Phosphorylation PhosphoSitePlus
T386 Phosphorylation PhosphoSitePlus
T617 Phosphorylation PhosphoSitePlus
S625 Phosphorylation PhosphoSitePlus
N655 N-Glycosylation GlyGen 24190977
T678 Phosphorylation PhosphoSitePlus
N700 N-Glycosylation GlyGen 29741879, 24190977
S702 Phosphorylation PhosphoSitePlus
N825 N-Glycosylation GlyGen 24190977
N842 N-Glycosylation GlyGen 29741879, 24190977
S897 Phosphorylation PhosphoSitePlus
Y991 Phosphorylation PhosphoSitePlus
S992 Phosphorylation PhosphoSitePlus
Y1176 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
T617 Phosphorylation HPRD 19413330
S625 Phosphorylation HPRD 19413330
S702 Phosphorylation HPRD 20068231
T1179 Phosphorylation HPRD 20068231
Site PTM Type PTM Enzyme Score Source PMID
T637 Phosphorylation HPRD 19413330
S645 Phosphorylation HPRD 19413330
S722 Phosphorylation HPRD 20068231
T1199 Phosphorylation HPRD 20068231


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S199 R199 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
T293 M293 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
T293 K293 Biomuta DOID:3571 / liver cancer [ cosmic ]
Y374 C374 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S897 F897 Biomuta DOID:4159 / skin cancer [ cosmic ]
S992 F992 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]