iPTMnet Report for O75052 (NOS1AP)


Protein Information

Cytoscape View


UniProt AC / UniProt ID O75052 / CAPON_HUMAN
Protein Name Carboxyl-terminal PDZ ligand of neuronal nitric oxide synthase protein
Gene Name Name: NOS1AP
Synonyms:CAPON,KIAA0464;
Organism Homo sapiens (Human)

PRO ID PR:O75052
DAG View
PRO Name carboxyl-terminal PDZ ligand of neuronal nitric oxide synthase protein (human)
Definition A carboxyl-terminal PDZ ligand of neuronal nitric oxide synthase protein that is encoded in the genome of human.
Short Label hNOS1AP
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


O75052 (NOS1AP) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T5 Phosphorylation PhosphoSitePlus
K6 Ubiquitination PhosphoSitePlus
Y7 Phosphorylation PhosphoSitePlus
K97 Ubiquitination PhosphoSitePlus
T100 Phosphorylation PhosphoSitePlus
Y114 Phosphorylation PhosphoSitePlus
S188 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S192 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S194 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S195 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
T203 Phosphorylation PhosphoSitePlus
T212 Phosphorylation PhosphoSitePlus
S249 Phosphorylation PhosphoSitePlus
T264 Phosphorylation phospho.ELM   PhosphoSitePlus 18220336
S266 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 23186163, 20068231, 18220336
S364 Phosphorylation PhosphoSitePlus
S371 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S374 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
T379 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S188 Phosphorylation HPRD 18669648
S192 Phosphorylation HPRD 18669648
S194 Phosphorylation HPRD 18669648
S195 Phosphorylation HPRD 18669648
T264 Phosphorylation HPRD 18691976
S266 Phosphorylation HPRD 18691976, 20068231
S371 Phosphorylation HPRD 18669648, 20068231
S374 Phosphorylation HPRD 18669648, 20068231


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T5 N5 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
T5 A5 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
K97 R97 Biomuta DOID:10283 / prostate cancer [ cosmic ]
T100 M100 Biomuta DOID:1319 / brain cancer [ icgc ] DOID:11054 / urinary bladder cancer [ cosmic ]
Y114 C114 Biomuta DOID:263 / kidney cancer [ cosmic ]
S266 L266 Biomuta DOID:4362 / cervical cancer [ cosmic ]
S371 F371 Biomuta DOID:4159 / skin cancer [ cosmic ]
S374 N374 Biomuta DOID:4159 / skin cancer [ cosmic ]