iPTMnet Report for O75051 (PLXNA2)
Protein Information
| UniProt AC / UniProt ID | O75051 / PLXA2_HUMAN |
| Protein Name | Plexin-A2 precursor |
| Gene Name | Name: PLXNA2 Synonyms:KIAA0463,OCT,PLXN2;ORFNames:UNQ209/PRO235; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:O75051 |
| PRO Name | plexin-A2 (human) |
| Definition | A plexin-A2 that is encoded in the genome of human. |
| Short Label | hPLXNA2 |
| Category | organism-gene |
O75051 (PLXNA2) as Substrate
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| Phosphorylation | score1 | PRO | ||||
| S15 | Phosphorylation | score1 | PhosphoSitePlus | |||
| N76 | N-Glycosylation | score1 | GlyGen | 24190977 | ||
| K138 | Acetylation | score1 | PhosphoSitePlus | |||
| K154 | Acetylation | score1 | PhosphoSitePlus | |||
| N163 | N-Glycosylation | score1 | GlyGen | 24190977 | ||
| Y293 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S295 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S434 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S444 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y470 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S474 | Phosphorylation | score1 | PhosphoSitePlus | |||
| N655 | N-Glycosylation | score1 | GlyGen | 24190977 | ||
| S850 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S1264 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K1272 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S1388 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K1424 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K1451 | Acetylation | score1 | PhosphoSitePlus | |||
| K1489 | Ubiquitination | score1 | PhosphoSitePlus | |||
| T1524 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y1605 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S1612 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 | ||
| Y1627 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T1628 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S1630 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S1633 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S1636 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S1670 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y1677 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K1685 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K1791 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K1797 | Ubiquitination | score1 | PhosphoSitePlus | |||
| Y1800 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S1806 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y1807 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y1814 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y1815 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S1825 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y1860 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S1861 | Phosphorylation | score1 | PhosphoSitePlus |
Proteoforms
| PRO ID (Short Label) | Sites | PTM Enzyme | Source | PMID | |
|---|---|---|---|---|---|
| PR:000048821 (hPLXNA2/SigPep-/PhosTyr+) | p | PRO |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| N655 | S655 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
| S1264 | Y1264 | Biomuta | DOID:3571 / liver cancer [ cosmic ] | |
| S1388 | L1388 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] DOID:4159 / skin cancer [ cosmic, icgc ] | |
| Y1605 | H1605 | Biomuta | DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ] | |
| T1628 | A1628 | Biomuta | DOID:8618 / oral cavity cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ] | |
| S1670 | N1670 | Biomuta | DOID:4362 / cervical cancer [ cosmic, icgc ] | |
| Y1800 | N1800 | Biomuta | DOID:3571 / liver cancer [ cosmic ] | |
| Y1800 | S1800 | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
| S1806 | N1806 | Biomuta | DOID:4159 / skin cancer [ cosmic ] |
DAG View