iPTMnet Report for O75037 (KIF21B)


Protein Information

Cytoscape View


UniProt AC / UniProt ID O75037 / KI21B_HUMAN
Protein Name Kinesin-like protein KIF21B
Gene Name Name: KIF21B
Synonyms:KIAA0449;
Organism Homo sapiens (Human)

PRO ID PR:O75037
DAG View
PRO Name kinesin-like protein KIF21B (human)
Definition A kinesin-like protein KIF21B that is encoded in the genome of human.
Short Label hKIF21B
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


O75037 (KIF21B) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
C75 Methylation IEDB 31844290
K205 Ubiquitination PhosphoSitePlus
K326 Ubiquitination PhosphoSitePlus
K380 Ubiquitination PhosphoSitePlus
Y417 Phosphorylation PhosphoSitePlus
S501 Phosphorylation PhosphoSitePlus
S510 O-Glycosylation GlyGen 28411811, 29351928
S562 Phosphorylation PhosphoSitePlus
K702 Acetylation PhosphoSitePlus
S739 Phosphorylation PhosphoSitePlus
S830 Phosphorylation PhosphoSitePlus
K910 Ubiquitination PhosphoSitePlus
T932 Phosphorylation PhosphoSitePlus
K1044 Ubiquitination PhosphoSitePlus
K1051 Ubiquitination PhosphoSitePlus
S1137 Phosphorylation PhosphoSitePlus
S1149 Phosphorylation PhosphoSitePlus   UniProt 23186163
S1167 Phosphorylation PhosphoSitePlus   UniProt 21406692, 23186163
S1197 Phosphorylation PhosphoSitePlus
R1201 Methylation PhosphoSitePlus
S1215 Phosphorylation PhosphoSitePlus   UniProt 23186163
S1222 Phosphorylation PhosphoSitePlus
T1237 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 21406692, 19690332
S1240 Phosphorylation PhosphoSitePlus
S1241 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 19690332
T1244 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S1258 Phosphorylation PhosphoSitePlus
S1261 Phosphorylation PhosphoSitePlus
S1269 Phosphorylation PhosphoSitePlus
S1272 Phosphorylation PhosphoSitePlus
S1275 Phosphorylation PhosphoSitePlus
S1285 Phosphorylation PhosphoSitePlus
S1421 Phosphorylation PhosphoSitePlus
T1490 Phosphorylation PhosphoSitePlus
K1528 Ubiquitination PhosphoSitePlus
K1584 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
T1237 Phosphorylation HPRD 18669648
S1241 Phosphorylation HPRD 18669648
T1244 Phosphorylation HPRD 18669648
S1258 Phosphorylation PhosphoSitePlus
S1261 Phosphorylation PhosphoSitePlus
S1264 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S501 F501 Biomuta DOID:4159 / skin cancer [ cosmic ]
K702 N702 Biomuta DOID:1324 / lung cancer [ cosmic ] DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ]
S1149 L1149 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S1167 F1167 Biomuta DOID:4159 / skin cancer [ cosmic ] DOID:3571 / liver cancer [ cosmic ]
S1222 P1222 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S1258 R1258 Biomuta DOID:1324 / lung cancer [ cosmic ]
S1285 F1285 Biomuta DOID:5041 / esophageal cancer [ cosmic, icgc ]
S1421 C1421 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]