iPTMnet Report for O75027 (ABCB7)
Protein Information
UniProt AC / UniProt ID | O75027 / ABCB7_HUMAN |
Protein Name | Iron-sulfur clusters transporter ABCB7, mitochondrial precursor |
Gene Name | Name: ABCB7 Synonyms:ABC7; |
Organism | Homo sapiens (Human) |
PRO ID | PR:O75027 |
PRO Name | iron-sulfur clusters transporter ABCB7, mitochondrial (human) |
Definition | An iron-sulfur clusters transporter ABCB7, mitochondrial that is encoded in the genome of human. |
Short Label | hABCB7 |
Category | organism-gene |
O75027 (ABCB7) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
R10 | Methylation | score1 | PhosphoSitePlus | |||
Y196 | Phosphorylation | score1 | PhosphoSitePlus | |||
S199 | Phosphorylation | score1 | PhosphoSitePlus | |||
K216 | Acetylation | score2 | PhosphoSitePlus UniProt | 19608861 | ||
K216 | Ubiquitination | score1 | PhosphoSitePlus | |||
S243 | Phosphorylation | score1 | PhosphoSitePlus | |||
K251 | Acetylation | score2 | PhosphoSitePlus UniProt | 19608861 | ||
K251 | Ubiquitination | score1 | PhosphoSitePlus | |||
T257 | Phosphorylation | score1 | PhosphoSitePlus | |||
S261 | Phosphorylation | score1 | PhosphoSitePlus | |||
S265 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y340 | Phosphorylation | score1 | PhosphoSitePlus | |||
K344 | Ubiquitination | score1 | PhosphoSitePlus | |||
S370 | Phosphorylation | score1 | PhosphoSitePlus | |||
T371 | Phosphorylation | score1 | PhosphoSitePlus | |||
T446 | Phosphorylation | score1 | PhosphoSitePlus | |||
S461 | O-Glycosylation | score1 | GlyGen | 30379171, 28510447, 29351928 | ||
T466 | O-Glycosylation | score1 | GlyGen | 30379171, 28510447, 29351928 | ||
S489 | Phosphorylation | score1 | PhosphoSitePlus | |||
S492 | Phosphorylation | score1 | PhosphoSitePlus | |||
K499 | Acetylation | score1 | PhosphoSitePlus | |||
K500 | Ubiquitination | score1 | PhosphoSitePlus | |||
S509 | O-Glycosylation | score1 | GlyGen | 30379171, 28510447, 29351928 | ||
T600 | Phosphorylation | score1 | PhosphoSitePlus | |||
K608 | Ubiquitination | score1 | PhosphoSitePlus | |||
S660 | Phosphorylation | score1 | PhosphoSitePlus | |||
S743 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
R10 | C10 | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
K499 | R499 | Biomuta | DOID:1324 / lung cancer [ cosmic, icgc ] | |
K500 | N500 | Biomuta | DOID:8618 / oral cavity cancer [ cosmic ] | |
K500 | R500 | Biomuta | DOID:363 / uterine cancer [ icgc ] |