iPTMnet Report for O75027 (ABCB7)


Protein Information

Cytoscape View


UniProt AC / UniProt ID O75027 / ABCB7_HUMAN
Protein Name Iron-sulfur clusters transporter ABCB7, mitochondrial precursor
Gene Name Name: ABCB7
Synonyms:ABC7;
Organism Homo sapiens (Human)

PRO ID PR:O75027
DAG View
PRO Name iron-sulfur clusters transporter ABCB7, mitochondrial (human)
Definition An iron-sulfur clusters transporter ABCB7, mitochondrial that is encoded in the genome of human.
Short Label hABCB7
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


O75027 (ABCB7) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
R10 Methylation PhosphoSitePlus
Y196 Phosphorylation PhosphoSitePlus
S199 Phosphorylation PhosphoSitePlus
K216 Acetylation PhosphoSitePlus   UniProt 19608861
K216 Ubiquitination PhosphoSitePlus
S243 Phosphorylation PhosphoSitePlus
K251 Acetylation PhosphoSitePlus   UniProt 19608861
K251 Ubiquitination PhosphoSitePlus
T257 Phosphorylation PhosphoSitePlus
S261 Phosphorylation PhosphoSitePlus
S265 Phosphorylation PhosphoSitePlus
Y340 Phosphorylation PhosphoSitePlus
K344 Ubiquitination PhosphoSitePlus
S370 Phosphorylation PhosphoSitePlus
T371 Phosphorylation PhosphoSitePlus
T446 Phosphorylation PhosphoSitePlus
S461 O-Glycosylation GlyGen 30379171, 28510447, 29351928
T466 O-Glycosylation GlyGen 30379171, 28510447, 29351928
S489 Phosphorylation PhosphoSitePlus
S492 Phosphorylation PhosphoSitePlus
K499 Acetylation PhosphoSitePlus
K500 Ubiquitination PhosphoSitePlus
S509 O-Glycosylation GlyGen 30379171, 28510447, 29351928
T600 Phosphorylation PhosphoSitePlus
K608 Ubiquitination PhosphoSitePlus
S660 Phosphorylation PhosphoSitePlus
S743 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S262 Phosphorylation HPRD 20068231
S266 Phosphorylation HPRD 20068231
S283 Phosphorylation HPRD 20068231
Y287 Phosphorylation HPRD 20068231
Y288 Phosphorylation HPRD 20068231


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
R10 C10 Biomuta DOID:1324 / lung cancer [ cosmic ]
K499 R499 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
K500 N500 Biomuta DOID:8618 / oral cavity cancer [ cosmic ]
K500 R500 Biomuta DOID:363 / uterine cancer [ icgc ]