iPTMnet Report for O75015 (FCGR3B)
Protein Information
| UniProt AC / UniProt ID | O75015 / FCG3B_HUMAN |
| Protein Name | Low affinity immunoglobulin gamma Fc region receptor III-B precursor |
| Gene Name | Name: FCGR3B Synonyms:CD16B,FCG3,FCGR3,IGFR3; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:O75015 |
| PRO Name | low affinity immunoglobulin gamma Fc region receptor III-B (human) |
| Definition | A low affinity immunoglobulin gamma Fc region receptor III-B that is encoded in the genome of human. |
| Short Label | hFCGR3B |
| Category | organism-gene |
DAG ViewO75015 (FCGR3B) as Substrate
 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| N82 | N-Glycosylation | score1 | GlyGen | 29741879 | ||
| T163 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S167 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S169 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y170 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| N82 | D82 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] DOID:1324 / lung cancer [ icgc ] DOID:2531 / hematologic cancer [ cosmic, icgc ] DOID:1781 / thyroid cancer [ icgc ] DOID:1793 / pancreatic cancer [ cosmic ] DOID:1781 / thyroid gland cancer [ cosmic ] DOID:8618 / oral cavity cancer [ cosmic ] | |
| S169 | F169 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
| S169 | C169 | Biomuta | DOID:1324 / lung cancer [ cosmic, icgc ] |
