iPTMnet Report for O70405 (Ulk1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID O70405 / ULK1_MOUSE
Protein Name Serine/threonine-protein kinase ULK1
Gene Name Name: Ulk1
Organism Mus musculus (Mouse)

PRO ID PR:O70405
DAG View
PRO Name serine/threonine-protein kinase ULK1 (mouse)
Definition A serine/threonine-protein kinase ULK1 that is encoded in the genome of mouse.
Short Label mULK1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


O70405 (Ulk1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S87 Phosphorylation PhosphoSitePlus
S147 Phosphorylation PhosphoSitePlus
K162 Acetylation PhosphoSitePlus   UniProt 22539723
R170 Methylation PhosphoSitePlus
T180 Phosphorylation PhosphoSitePlus
S195 Phosphorylation PhosphoSitePlus
S224 Phosphorylation PhosphoSitePlus
L255 Phosphorylation IntAct 25980607
S281 Phosphorylation PhosphoSitePlus
T282 Phosphorylation PhosphoSitePlus
S317 Phosphorylation PhosphoSitePlus   RLIMS-P   UniProt 25991723, 21258367, 24389528, ...28492544, 27387347, 27887947, 26869683, 30729040, 31865844
S341 Phosphorylation PhosphoSitePlus
S403 Phosphorylation PhosphoSitePlus
S405 Phosphorylation PhosphoSitePlus
S415 Phosphorylation PhosphoSitePlus
S450 Phosphorylation PhosphoSitePlus   UniProt 21183079
S459 Phosphorylation PhosphoSitePlus
S460 Phosphorylation PhosphoSitePlus
S465 Phosphorylation PhosphoSitePlus
S467 Phosphorylation PhosphoSitePlus   UniProt 21205641
T468 Phosphorylation PhosphoSitePlus
T469 Phosphorylation PhosphoSitePlus
S477 Phosphorylation PhosphoSitePlus
S479 Phosphorylation PhosphoSitePlus
S482 Phosphorylation PhosphoSitePlus
S494 Phosphorylation PhosphoSitePlus
S504 Phosphorylation PhosphoSitePlus
S521 Phosphorylation PhosphoSitePlus   UniProt 21183079
S532 Phosphorylation PhosphoSitePlus
S537 Phosphorylation PhosphoSitePlus
S543 Phosphorylation PhosphoSitePlus
S555 Phosphorylation PhosphoSitePlus   RLIMS-P   UniProt 27887947, 33128669, 26556533, ...27119351, 24389528, 29540819, 31594991, 25905437, 30022064, 31865844, 28916822, 31469345, 34074127, 31005723, 24732703, 29348566, 29732320, 24988326, 30112966, 25071026, 27387347, 30729040, 30544824, 32299471, 21205641, 31225455, 26039451, 27464336, 33800526, 24449471
T574 Phosphorylation PhosphoSitePlus   UniProt 21205641
S582 O-Glycosylation GlyGen 32782141
S597 Phosphorylation PhosphoSitePlus
K606 Acetylation PhosphoSitePlus   UniProt 22539723
S614 Phosphorylation PhosphoSitePlus
S622 Phosphorylation PhosphoSitePlus
T624 Phosphorylation phospho.ELM   PhosphoSitePlus 17242355
S629 Phosphorylation PhosphoSitePlus
T635 O-Glycosylation PhosphoSitePlus
T635 Phosphorylation PhosphoSitePlus   UniProt 21183079
S637 Phosphorylation phospho.ELM   PhosphoSitePlus   RLIMS-P   UniProt 21183079, 32273498, 21205641, ...17242355
S638 Phosphorylation PhosphoSitePlus   UniProt 21183079
T653 Phosphorylation PhosphoSitePlus
T659 Phosphorylation PhosphoSitePlus
S693 Phosphorylation PhosphoSitePlus
S713 Phosphorylation PhosphoSitePlus
S715 Phosphorylation PhosphoSitePlus
T716 Phosphorylation PhosphoSitePlus
S718 Phosphorylation PhosphoSitePlus
S746 Phosphorylation PhosphoSitePlus   RLIMS-P 32273498
S747 Phosphorylation PhosphoSitePlus
T754 O-Glycosylation PhosphoSitePlus
S757 Phosphorylation PhosphoSitePlus   RLIMS-P   UniProt 32987187, 29540819, 27119351, ...27343428, 27314664, 24389528, 28492544, 27887947, 24187137, 26487002, 32512189, 21183079, 30022064, 32207633, 28916822, 27617292, 25780086, 23964069, 31005723, 27246695, 33459523, 27387347, 33562139, 30729040, 31261758, 21258367, 26039451, 26869683, 33800526, 28674405
S760 Phosphorylation PhosphoSitePlus
T763 Phosphorylation PhosphoSitePlus
S774 Phosphorylation PhosphoSitePlus
S777 Phosphorylation PhosphoSitePlus   RLIMS-P   UniProt 32512189, 21258367, 27314664, ...28492544, 27387347, 28674405, 33562139
S780 Phosphorylation PhosphoSitePlus
S867 Phosphorylation PhosphoSitePlus
S913 Phosphorylation PhosphoSitePlus
S950 Phosphorylation PhosphoSitePlus
S983 Phosphorylation PhosphoSitePlus
S991 Phosphorylation PhosphoSitePlus
S1043 Phosphorylation PhosphoSitePlus
S1047 Phosphorylation PhosphoSitePlus


O70405 (Ulk1) as PTM Enzyme



Substrate Site Score Source PMID
O88597 (Becn1) S14 PhosphoSitePlus 23685627


PTM-dependent PPI

PTM type Substrate Site Interactant Association type Source PMID
Phosphorylation O70405 (Ulk1) S757 P54646 (PRKAA2) inhibited_association eFIP 33562139
Phosphorylation O70405 (Ulk1) S555 Q9JLN9 (Mtor) inhibited_association eFIP 29348566
Phosphorylation O70405 (Ulk1) S757 Q68ED7 (Crtc1) unknown eFIP 30022064