Protein Information

Cytoscape View

UniProt AC / UniProt ID O60938 / KERA_HUMAN
Protein Name Keratocan precursor
Gene Name Name: KERA
Organism Homo sapiens (Human)

PRO ID PR:O60938
DAG View
PRO Name keratocan (human)
Definition A keratocan that is encoded in the genome of human.
Short Label hKERA
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species

O60938 (KERA) as Substrate

Site PTM Type PTM Enzyme Score Source PMID
K104 Acetylation PhosphoSitePlus
K106 Acetylation PhosphoSitePlus
T108 Phosphorylation PhosphoSitePlus
Y110 Phosphorylation PhosphoSitePlus
S118 Phosphorylation PhosphoSitePlus
S256 Phosphorylation PhosphoSitePlus
N298 N-Glycosylation UniProt 16335952
Y324 Phosphorylation PhosphoSitePlus
T342 Phosphorylation PhosphoSitePlus

PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K104 Q104 Biomuta DOID:1324 / lung cancer [ cosmic ]
K104 E104 Biomuta DOID:9256 / colorectal cancer [ icgc ]
K106 N106 Biomuta DOID:1793 / pancreatic cancer [ tcga ] DOID:3571 / liver cancer [ icgc ] DOID:0070003 / blastoma [ cosmic ]
S118 R118 Biomuta DOID:3571 / liver cancer [ icgc ]
S256 * Biomuta DOID:11054 / urinary bladder cancer [ tcga ]
S256 L256 Biomuta DOID:1909 / melanoma [ icgc, tcga ]
S256 A256 Biomuta DOID:1909 / melanoma [ tcga ]
T342 A342 Biomuta DOID:10283 / prostate cancer [ cosmic, icgc ]