iPTMnet Report for O60930 (RNASEH1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID O60930 / RNH1_HUMAN
Protein Name Ribonuclease H1
Gene Name Name: RNASEH1
Synonyms:RNH1;
Organism Homo sapiens (Human)

PRO ID PR:O60930
DAG View
PRO Name ribonuclease H1 (human)
Definition A ribonuclease H1 that is encoded in the genome of human.
Short Label hRNASEH1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


O60930 (RNASEH1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S22 Phosphorylation PhosphoSitePlus
R52 Methylation PhosphoSitePlus
K60 Ubiquitination PhosphoSitePlus
K73 Ubiquitination PhosphoSitePlus
S74 Phosphorylation HPRD   PhosphoSitePlus 19651622
S76 Phosphorylation HPRD   PhosphoSitePlus 19651622
K119 Ubiquitination PhosphoSitePlus
R175 Methylation PhosphoSitePlus
K192 Ubiquitination PhosphoSitePlus
K198 Ubiquitination PhosphoSitePlus
K236 Ubiquitination PhosphoSitePlus
K241 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S22 F22 Biomuta DOID:11054 / urinary bladder cancer [ cosmic ]
S22 C22 Biomuta DOID:8618 / oral cavity cancer [ cosmic ] DOID:5041 / esophageal cancer [ cosmic ] DOID:1324 / lung cancer [ cosmic, icgc ]
K60 N60 Biomuta DOID:1324 / lung cancer [ icgc ]
R175 I175 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]