Protein Information

Cytoscape View


UniProt AC / UniProt ID O60890 / OPHN1_HUMAN
Protein Name Oligophrenin-1
Gene Name Name: OPHN1
Organism Homo sapiens (Human)

PRO ID PR:O60890
DAG View
PRO Name oligophrenin-1 (human)
Definition An oligophrenin-1 that is encoded in the genome of human.
Short Label hOPHN1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


O60890 (OPHN1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K37 Acetylation PhosphoSitePlus
K121 Ubiquitination PhosphoSitePlus
Y370 Phosphorylation PhosphoSitePlus
S372 Phosphorylation PhosphoSitePlus
Y480 Phosphorylation PhosphoSitePlus
T531 Phosphorylation PhosphoSitePlus
S652 Phosphorylation PhosphoSitePlus
T685 Phosphorylation PhosphoSitePlus
S696 Phosphorylation PhosphoSitePlus
S703 Phosphorylation PhosphoSitePlus
S724 Phosphorylation PhosphoSitePlus
T753 Phosphorylation PhosphoSitePlus
S802 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S652 Phosphorylation HPRD 19651622


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K37 R37 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
K37 T37 Biomuta DOID:363 / uterine cancer [ cosmic, icgc, tcga ]
S372 R372 Biomuta DOID:3571 / liver cancer [ icgc ]
S703 Y703 Biomuta DOID:1324 / lung cancer [ cosmic ]