iPTMnet Report for O60826 (CCDC22)


Protein Information

Cytoscape View


UniProt AC / UniProt ID O60826 / CCD22_HUMAN
Protein Name Coiled-coil domain-containing protein 22
Gene Name Name: CCDC22
Synonyms:CXorf37;ORFNames:JM1;
Organism Homo sapiens (Human)

PRO ID PR:O60826
DAG View
PRO Name coiled-coil domain-containing protein 22 (human)
Definition A coiled-coil domain-containing protein 22 that is encoded in the genome of human.
Short Label hCCDC22
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


O60826 (CCDC22) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S51 Phosphorylation PhosphoSitePlus
S70 Phosphorylation PhosphoSitePlus
K162 Ubiquitination PhosphoSitePlus
K250 Ubiquitination PhosphoSitePlus
T253 Phosphorylation PhosphoSitePlus
K284 Ubiquitination PhosphoSitePlus
K298 Ubiquitination PhosphoSitePlus
S347 Phosphorylation PhosphoSitePlus
K373 Ubiquitination PhosphoSitePlus
K386 Ubiquitination PhosphoSitePlus
K402 Ubiquitination PhosphoSitePlus
S410 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 18088087
K423 Ubiquitination PhosphoSitePlus
Y474 Phosphorylation PhosphoSitePlus
K513 Ubiquitination PhosphoSitePlus
K519 Ubiquitination PhosphoSitePlus
K523 Ubiquitination PhosphoSitePlus
S527 O-Glycosylation GlyGen 34019948, 29351928
S527 Phosphorylation PhosphoSitePlus
S529 O-Glycosylation GlyGen 34019948, 29351928
S529 Phosphorylation PhosphoSitePlus
K531 Ubiquitination PhosphoSitePlus
K545 Ubiquitination PhosphoSitePlus
C567 Methylation IEDB 31844290
K597 Ubiquitination PhosphoSitePlus
K598 Ubiquitination PhosphoSitePlus
T599 Phosphorylation PhosphoSitePlus
S601 Phosphorylation PhosphoSitePlus
K605 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K298 E298 Biomuta DOID:4159 / skin cancer [ cosmic ]
S529 F529 Biomuta DOID:5041 / esophageal cancer [ cosmic, icgc ]