iPTMnet Report for O60784 (TOM1)
Protein Information
UniProt AC / UniProt ID | O60784 / TOM1_HUMAN |
Protein Name | Target of Myb1 membrane trafficking protein |
Gene Name | Name: TOM1 |
Organism | Homo sapiens (Human) |
PRO ID | PR:O60784 |
PRO Name | target of Myb1 membrane trafficking protein (human) |
Definition | A target of Myb1 membrane trafficking protein that is encoded in the genome of human. |
Short Label | hTOM1 |
Category | organism-gene |
O60784 (TOM1) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
M1 | Acetylation | score1 | UniProt | 22814378, 22223895, 20068231 | ||
S10 | Phosphorylation | score1 | PhosphoSitePlus | |||
S11 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 20068231 | ||
K106 | Ubiquitination | score1 | PhosphoSitePlus | |||
K116 | Ubiquitination | score1 | PhosphoSitePlus | |||
S130 | Phosphorylation | score1 | PhosphoSitePlus | |||
S131 | Phosphorylation | score1 | PhosphoSitePlus | |||
T135 | Phosphorylation | score1 | PhosphoSitePlus | |||
T139 | Phosphorylation | score1 | PhosphoSitePlus | |||
K147 | Ubiquitination | score1 | PhosphoSitePlus | |||
T154 | Phosphorylation | score1 | PhosphoSitePlus | |||
S160 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus UniProt | 18669648, 19690332, 20068231 | ||
T164 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus UniProt | 18669648, 19690332, 20068231 | ||
S222 | Phosphorylation | score1 | PhosphoSitePlus | |||
K311 | Ubiquitination | score1 | PhosphoSitePlus | |||
S314 | Phosphorylation | score1 | PhosphoSitePlus | |||
S355 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus UniProt | 21406692, 23186163, 18669648, ... | ||
S359 | Phosphorylation | score1 | PhosphoSitePlus | |||
S376 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 24275569 | ||
K382 | Ubiquitination | score1 | PhosphoSitePlus | |||
K385 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y386 | Phosphorylation | score1 | PhosphoSitePlus | |||
S405 | Phosphorylation | score1 | PhosphoSitePlus | |||
T406 | Phosphorylation | score1 | PhosphoSitePlus | |||
K445 | Ubiquitination | score1 | PhosphoSitePlus | |||
K452 | Ubiquitination | score1 | PhosphoSitePlus | |||
S461 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 24275569 | ||
S462 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus UniProt | 18669648 | ||
S464 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus | 18669648 | ||
S473 | Phosphorylation | score1 | PhosphoSitePlus | |||
T481 | Phosphorylation | score1 | PhosphoSitePlus | |||
K484 | Ubiquitination | score1 | PhosphoSitePlus |
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
S11 | Phosphorylation | score0 | HPRD | 20068231 | ||
T154 | Phosphorylation | score0 | HPRD | 17081983, 20068231 | ||
S160 | Phosphorylation | score0 | HPRD | 19651622, 18669648, 20068231 | ||
T164 | Phosphorylation | score0 | HPRD | 19651622, 18669648, 17081983, ... | ||
S355 | Phosphorylation | score0 | HPRD | 17322306, 18669648, 20058876, ... | ||
S359 | Phosphorylation | score0 | HPRD | 19664994 | ||
S461 | Phosphorylation | score0 | HPRD | 19415658, 20068231, 17924679 | ||
S462 | Phosphorylation | score0 | HPRD | 18669648, 17081983, 20068231 | ||
S464 | Phosphorylation | score0 | HPRD | 18669648, 20068231, 17924679 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
K443 | Ubiquitination | score1 | PhosphoSitePlus |
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
K410 | Ubiquitination | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
S11 | F11 | Biomuta | DOID:363 / uterine cancer [ icgc ] | |
S131 | L131 | Biomuta | DOID:4159 / skin cancer [ cosmic, icgc ] DOID:10534 / stomach cancer [ cosmic ] | |
S222 | R222 | Biomuta | DOID:363 / uterine cancer [ icgc ] | |
S405 | I405 | Biomuta | DOID:1319 / brain cancer [ icgc ] | |
T406 | A406 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] |