iPTMnet Report for O60762 (DPM1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID O60762 / DPM1_HUMAN
Protein Name Dolichol-phosphate mannosyltransferase subunit 1
Gene Name Name: DPM1
Organism Homo sapiens (Human)

PRO ID PR:O60762
DAG View
PRO Name dolichol-phosphate mannosyltransferase subunit 1 (human)
Definition A dolichol-phosphate mannosyltransferase subunit 1 that is encoded in the genome of human.
Short Label hDPM1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


O60762 (DPM1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
A2 Acetylation UniProt 21406692, 22814378, 20068231
S3 Phosphorylation HPRD   PhosphoSitePlus   UniProt 23186163, 17081983, 19007248
S7 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 18691976, 17081983, 19007248
S9 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 18691976, 21406692, 23186163, ...17081983, 18578522, 19691289, 19651622, 19007248, 20068231
S21 Phosphorylation HPRD   PhosphoSitePlus 18691976, 20068231
K26 Ubiquitination PhosphoSitePlus
Y27 Phosphorylation PhosphoSitePlus
S28 Phosphorylation PhosphoSitePlus
K80 Ubiquitination PhosphoSitePlus
K95 Ubiquitination PhosphoSitePlus
Y102 Phosphorylation PhosphoSitePlus
Y113 Phosphorylation PhosphoSitePlus
K136 Ubiquitination PhosphoSitePlus
K149 Methylation PhosphoSitePlus
K149 Ubiquitination PhosphoSitePlus
K160 Ubiquitination PhosphoSitePlus
K197 Acetylation PhosphoSitePlus
K197 Ubiquitination PhosphoSitePlus
K201 Ubiquitination PhosphoSitePlus
R234 Methylation PhosphoSitePlus
K240 Ubiquitination PhosphoSitePlus
S248 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
A2 V2 Biomuta DOID:4159 / skin cancer [ cosmic ]
S3 F3 Biomuta DOID:4159 / skin cancer [ cosmic ]
S7 G7 Biomuta DOID:1793 / pancreatic cancer [ cosmic ]
S7 N7 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
S21 G21 Biomuta DOID:1793 / pancreatic cancer [ cosmic ]
K80 N80 Biomuta DOID:3571 / liver cancer [ cosmic ]
K136 N136 Biomuta DOID:363 / uterine cancer [ icgc ]
K136 * Biomuta DOID:1324 / lung cancer [ cosmic ]
R234 C234 Biomuta DOID:8618 / oral cavity cancer [ cosmic ]
R234 H234 Biomuta DOID:10534 / stomach cancer [ cosmic ]
S248 Y248 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S248 C248 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]