iPTMnet Report for O60739 (EIF1B)


Protein Information

Cytoscape View


UniProt AC / UniProt ID O60739 / EIF1B_HUMAN
Protein Name Eukaryotic translation initiation factor 1b
Gene Name Name: EIF1B
Organism Homo sapiens (Human)

PRO ID PR:O60739
DAG View
PRO Name eukaryotic translation initiation factor 1b (human)
Definition A eukaryotic translation initiation factor 1b that is encoded in the genome of human.
Short Label hEIF1B
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


O60739 (EIF1B) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S2 Acetylation UniProt 21406692
S9 Phosphorylation PhosphoSitePlus   UniProt 21406692, 23186163
K18 Ubiquitination PhosphoSitePlus
T27 Phosphorylation PhosphoSitePlus
Y30 Phosphorylation PhosphoSitePlus
K42 Ubiquitination PhosphoSitePlus
T43 Phosphorylation PhosphoSitePlus
K58 Acetylation PhosphoSitePlus
K61 Acetylation PhosphoSitePlus
K66 Ubiquitination PhosphoSitePlus
Y79 Phosphorylation PhosphoSitePlus
K91 Ubiquitination PhosphoSitePlus
K104 Sumoylation PhosphoSitePlus
K109 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S9 Y9 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
K18 N18 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
K42 Q42 Biomuta DOID:10534 / stomach cancer [ cosmic ]