iPTMnet Report for O60711 (LPXN)


Protein Information

Cytoscape View


UniProt AC / UniProt ID O60711 / LPXN_HUMAN
Protein Name Leupaxin
Gene Name Name: LPXN
Synonyms:LDLP;
Organism Homo sapiens (Human)

PRO ID PR:O60711
DAG View
PRO Name leupaxin (human)
Definition A leupaxin that is encoded in the genome of human.
Short Label hLPXN
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


O60711 (LPXN) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
M1 Acetylation UniProt 22814378, 25944712
S14 Phosphorylation PhosphoSitePlus
T15 Phosphorylation PhosphoSitePlus
S19 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 15144186
Y22 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 15592455, 20543562, 15144186, ...16094384
S23 Phosphorylation PhosphoSitePlus
S34 Phosphorylation PhosphoSitePlus
Y62 Phosphorylation PhosphoSitePlus   UniProt 20543562
Y72 Phosphorylation P07948 (LYN) neXtProt   PhosphoSitePlus   RLIMS-P   Signor   UniProt 20543562, 17640867
S81 Phosphorylation PhosphoSitePlus   UniProt 24275569
K86 Ubiquitination PhosphoSitePlus
K106 Ubiquitination PhosphoSitePlus
K121 Ubiquitination PhosphoSitePlus
K125 Ubiquitination PhosphoSitePlus
S127 Phosphorylation PhosphoSitePlus
S130 Phosphorylation PhosphoSitePlus
K149 Ubiquitination PhosphoSitePlus
K157 Ubiquitination PhosphoSitePlus
S170 Phosphorylation PhosphoSitePlus
S187 Phosphorylation PhosphoSitePlus
S188 Phosphorylation PhosphoSitePlus
S194 Phosphorylation PhosphoSitePlus
C199 Methylation IEDB 31844290
Y203 Phosphorylation PhosphoSitePlus
S208 Phosphorylation PhosphoSitePlus
C211 Methylation IEDB 31844290
Y213 Phosphorylation PhosphoSitePlus
C214 Methylation IEDB 31844290
C258 Methylation IEDB 31844290
K260 Ubiquitination PhosphoSitePlus
S267 Phosphorylation PhosphoSitePlus
C293 Methylation IEDB 31844290
T327 Phosphorylation PhosphoSitePlus
S342 Phosphorylation PhosphoSitePlus
K364 Ubiquitination PhosphoSitePlus
K373 Ubiquitination PhosphoSitePlus
Y375 Phosphorylation PhosphoSitePlus
K382 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S19 Phosphorylation HPRD 15144186
Y22 Phosphorylation HPRD 15144186


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S81 L81 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
K106 R106 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
K121 N121 Biomuta DOID:263 / kidney cancer [ cosmic, icgc ]
S127 F127 Biomuta DOID:4159 / skin cancer [ cosmic ]
S194 G194 Biomuta DOID:10534 / stomach cancer [ cosmic ]
S208 P208 Biomuta DOID:1319 / brain cancer [ cosmic ]
Y213 D213 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
S267 * Biomuta DOID:11054 / urinary bladder cancer [ cosmic ]
S267 L267 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
T327 M327 Biomuta DOID:363 / uterine cancer [ cosmic ] DOID:4159 / skin cancer [ cosmic ]
K364 N364 Biomuta DOID:2021 / placenta cancer [ cosmic ]
Y375 C375 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]