iPTMnet Report for O60704 (TPST2)


Protein Information

Cytoscape View


UniProt AC / UniProt ID O60704 / TPST2_HUMAN
Protein Name Protein-tyrosine sulfotransferase 2
Gene Name Name: TPST2
Organism Homo sapiens (Human)

PRO ID PR:O60704
DAG View
PRO Name protein-tyrosine sulfotransferase 2 (human)
Definition A protein-tyrosine sulfotransferase 2 that is encoded in the genome of human.
Short Label hTPST2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


O60704 (TPST2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
N58 N-Glycosylation GlyGen 24190977
K158 Ubiquitination PhosphoSitePlus
S188 Phosphorylation PhosphoSitePlus
S191 Phosphorylation PhosphoSitePlus
T194 Phosphorylation PhosphoSitePlus
Y222 Phosphorylation PhosphoSitePlus
S278 O-Glycosylation GlyGen   PhosphoSitePlus 23584533, 25813380
S285 O-Glycosylation GlyGen   PhosphoSitePlus 23584533, 25813380
T286 O-Glycosylation GlyGen   PhosphoSitePlus 23584533, 30459171, 25813380
K291 Ubiquitination PhosphoSitePlus
N366 N-Glycosylation GlyGen 24190977
N368 N-Glycosylation GlyGen 24190977


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
N58 S58 Biomuta DOID:363 / uterine cancer [ icgc ]
S191 F191 Biomuta [ cosmic ] DOID:1115 / sarcoma [ icgc ]
K291 E291 Biomuta DOID:10534 / stomach cancer [ cosmic ]