iPTMnet Report for O60684 (KPNA6)


Protein Information

Cytoscape View


UniProt AC / UniProt ID O60684 / IMA7_HUMAN
Protein Name Importin subunit alpha-7
Gene Name Name: KPNA6
Synonyms:IPOA7;
Organism Homo sapiens (Human)

PRO ID PR:O60684
DAG View
PRO Name importin subunit alpha-7 (human)
Definition An importin subunit alpha-7 that is encoded in the genome of human.
Short Label hKPNA6
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


O60684 (KPNA6) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
M1 Acetylation UniProt 19413330, 22814378, 20068231
T3 Phosphorylation HPRD   PhosphoSitePlus 19413330, 20068231
S6 Phosphorylation HPRD   PhosphoSitePlus   UniProt 19413330, 18691976, 23186163, ...19691289, 19651622, 20068231
K9 Ubiquitination PhosphoSitePlus
S16 Phosphorylation PhosphoSitePlus
K18 Acetylation PhosphoSitePlus
K18 Ubiquitination PhosphoSitePlus
K49 Ubiquitination PhosphoSitePlus
S91 Phosphorylation PhosphoSitePlus
T100 Phosphorylation PhosphoSitePlus
T101 Phosphorylation PhosphoSitePlus
K110 Ubiquitination PhosphoSitePlus
S113 Phosphorylation HPRD   PhosphoSitePlus   UniProt 23186163, 20068231
T122 Phosphorylation PhosphoSitePlus
R128 Methylation PhosphoSitePlus
K134 Ubiquitination PhosphoSitePlus
S235 Phosphorylation PhosphoSitePlus
K241 Ubiquitination PhosphoSitePlus
K249 Ubiquitination PhosphoSitePlus
Y308 Phosphorylation PhosphoSitePlus
K354 Ubiquitination PhosphoSitePlus
T359 Phosphorylation PhosphoSitePlus
S361 Phosphorylation PhosphoSitePlus
K396 Ubiquitination PhosphoSitePlus
K457 Ubiquitination PhosphoSitePlus
Y474 Phosphorylation PhosphoSitePlus
K478 Ubiquitination PhosphoSitePlus
Y491 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S16 T16 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
K49 Q49 Biomuta DOID:363 / uterine cancer [ icgc ]
S91 F91 Biomuta DOID:4159 / skin cancer [ cosmic ]
S91 Y91 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
R128 W128 Biomuta DOID:4159 / skin cancer [ cosmic ] DOID:1324 / lung cancer [ cosmic ]
R128 Q128 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
Y491 C491 Biomuta DOID:9256 / colorectal cancer [ cosmic ]