iPTMnet Report for O60669 (SLC16A7)


Protein Information

Cytoscape View


UniProt AC / UniProt ID O60669 / MOT2_HUMAN
Protein Name Monocarboxylate transporter 2
Gene Name Name: SLC16A7
Synonyms:MCT2;
Organism Homo sapiens (Human)

PRO ID PR:O60669
DAG View
PRO Name monocarboxylate transporter 2 (human)
Definition A monocarboxylate transporter 2 that is encoded in the genome of human.
Short Label hSLC16A7
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


O60669 (SLC16A7) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S33 Phosphorylation PhosphoSitePlus
Y34 Phosphorylation PhosphoSitePlus
S62 Phosphorylation PhosphoSitePlus
S218 Phosphorylation HPRD   PhosphoSitePlus 19651622
K221 Ubiquitination PhosphoSitePlus
K232 Ubiquitination PhosphoSitePlus
K444 Ubiquitination PhosphoSitePlus
T445 Phosphorylation PhosphoSitePlus
S448 Phosphorylation PhosphoSitePlus
K453 Ubiquitination PhosphoSitePlus
K455 Ubiquitination PhosphoSitePlus
S457 Phosphorylation PhosphoSitePlus
K463 Ubiquitination PhosphoSitePlus
S465 O-Glycosylation GlyGen 28510447, 28657654, 35254053
S465 Phosphorylation PhosphoSitePlus
S469 Phosphorylation PhosphoSitePlus
S472 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
Y34 C34 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S62 P62 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
S218 * Biomuta DOID:4159 / skin cancer [ cosmic ]
K221 N221 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
K232 N232 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
T445 N445 Biomuta DOID:4606 / bile duct cancer [ cosmic ]
T445 S445 Biomuta DOID:9256 / colorectal cancer [ cosmic ] DOID:2531 / hematologic cancer [ cosmic ]
S457 L457 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S465 * Biomuta DOID:4362 / cervical cancer [ cosmic ]