iPTMnet Report for O60637 (TSPAN3)


Protein Information

Cytoscape View


UniProt AC / UniProt ID O60637 / TSN3_HUMAN
Protein Name Tetraspanin-3
Gene Name Name: TSPAN3
Synonyms:TM4SF8;
Organism Homo sapiens (Human)

PRO ID PR:O60637
DAG View
PRO Name tetraspanin-3 (human)
Definition A tetraspanin-3 that is encoded in the genome of human.
Short Label hTSPAN3
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


O60637 (TSPAN3) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K124 Ubiquitination PhosphoSitePlus
T125 Phosphorylation PhosphoSitePlus
Y126 Phosphorylation PhosphoSitePlus
N127 N-Glycosylation GlyGen 23090970, 29741879, 23345538, ...24190977
T129 Phosphorylation PhosphoSitePlus
N130 N-Glycosylation GlyGen 24190977
N152 N-Glycosylation GlyGen 24190977
N158 N-Glycosylation GlyGen 24190977
N167 N-Glycosylation GlyGen 23090970, 29741879, 24190977
S169 Phosphorylation PhosphoSitePlus
S173 O-Glycosylation GlyGen 32119511, 35289036, 34725712
S173 Phosphorylation PhosphoSitePlus
N183 N-Glycosylation GlyGen 24190977
S185 Phosphorylation PhosphoSitePlus
Y243 Phosphorylation PhosphoSitePlus
T248 Phosphorylation PhosphoSitePlus
Y252 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
N127 N-Glycosylation PRO 23345538


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
N127 S127 Biomuta DOID:8618 / oral cavity cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ]
N130 K130 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
T248 N248 Biomuta DOID:3571 / liver cancer [ cosmic ]