iPTMnet Report for O60603 (TLR2)
Protein Information
| UniProt AC / UniProt ID | O60603 / TLR2_HUMAN |
| Protein Name | Toll-like receptor 2 precursor |
| Gene Name | Name: TLR2 Synonyms:TIL4; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:O60603 |
| PRO Name | Toll-like receptor 2 (human) |
| Definition | A Toll-like receptor 2 that is encoded in the genome of human. |
| Short Label | hTLR2 |
| Category | organism-gene |
DAG ViewO60603 (TLR2) as Substrate
 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| S45 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S48 | Phosphorylation | score1 | PhosphoSitePlus | |||
| N114 | N-Glycosylation | score4 | GlyGen UniProt | 17889651, 15173186 | ||
| T138 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T142 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S143 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S193 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S196 | Phosphorylation | score1 | PhosphoSitePlus | |||
| N199 | N-Glycosylation | score4 | GlyGen UniProt | 17889651, 15173186, 32125861, ... | ||
| T262 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y323 | Phosphorylation | score1 | PhosphoSitePlus | |||
| N414 | N-Glycosylation | score4 | GlyGen UniProt | 29741879, 17889651, 32125861 | ||
| N442 | N-Glycosylation | score4 | GlyGen UniProt | 17889651, 15173186, 24190977 | ||
| Y653 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K754 | Ubiquitination | score2 | UniProt | 27805901 |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| S48 | * | Biomuta | DOID:5041 / esophageal cancer [ cosmic ] | |
| S48 | A48 | Biomuta | DOID:5041 / esophageal cancer [ cosmic ] |
