iPTMnet Report for O60573 (EIF4E2)
Protein Information
| UniProt AC / UniProt ID | O60573 / IF4E2_HUMAN |
| Protein Name | Eukaryotic translation initiation factor 4E type 2 |
| Gene Name | Name: EIF4E2 Synonyms:EIF4EL3; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:O60573 |
| PRO Name | eukaryotic translation initiation factor 4E type 2 (human) |
| Definition | A eukaryotic translation initiation factor 4E type 2 that is encoded in the genome of human. |
| Short Label | hEIF4E2 |
| Category | organism-gene |
DAG ViewO60573 (EIF4E2) as Substrate
 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| S13 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 | ||
| T68 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S75 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K121 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K134 | Acetylation | score2 | PhosphoSitePlus UniProt | 19608861 | ||
| K239 | Ubiquitination | score1 | PhosphoSitePlus | |||
| R241 | Methylation | score1 | PhosphoSitePlus |
|
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| K222 | Ubiquitination | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| R241 | W241 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] DOID:1612 / breast cancer [ cosmic ] |
