iPTMnet Report for O60551 (NMT2)
Protein Information
UniProt AC / UniProt ID | O60551 / NMT2_HUMAN |
Protein Name | Glycylpeptide N-tetradecanoyltransferase 2 |
Gene Name | Name: NMT2 |
Organism | Homo sapiens (Human) |
PRO ID | PR:O60551 |
PRO Name | glycylpeptide N-tetradecanoyltransferase 2 (human) |
Definition | A glycylpeptide N-tetradecanoyltransferase 2 that is encoded in the genome of human. |
Short Label | hNMT2 |
Category | organism-gene |
O60551 (NMT2) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
S7 | Phosphorylation | score1 | PhosphoSitePlus | |||
S38 | Phosphorylation | score2 | HPRD PhosphoSitePlus UniProt | 19413330, 23186163, 24275569 | ||
S61 | Phosphorylation | score1 | PhosphoSitePlus | |||
T64 | Phosphorylation | score1 | PhosphoSitePlus | |||
S66 | Phosphorylation | score1 | PhosphoSitePlus | |||
S68 | Phosphorylation | score1 | PhosphoSitePlus | |||
S70 | Phosphorylation | score1 | PhosphoSitePlus | |||
K144 | Ubiquitination | score1 | PhosphoSitePlus | |||
S229 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y283 | Phosphorylation | score1 | PhosphoSitePlus | |||
S302 | Phosphorylation | score1 | PhosphoSitePlus | |||
K327 | Ubiquitination | score1 | PhosphoSitePlus | |||
T337 | Phosphorylation | score0 | HPRD | 20068231 | ||
S338 | Phosphorylation | score0 | HPRD | 20068231 | ||
K447 | Ubiquitination | score1 | PhosphoSitePlus | |||
K461 | Ubiquitination | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
S61 | F61 | Biomuta | DOID:4159 / skin cancer [ cosmic ] DOID:4362 / cervical cancer [ cosmic, icgc ] | |
K327 | N327 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] | |
K447 | * | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
K461 | N461 | Biomuta | DOID:11054 / urinary bladder cancer [ cosmic, icgc ] |