iPTMnet Report for O60524 (NEMF)


Protein Information

Cytoscape View


UniProt AC / UniProt ID O60524 / NEMF_HUMAN
Protein Name Ribosome quality control complex subunit NEMF
Gene Name Name: NEMF
Synonyms:SDCCAG1;
Organism Homo sapiens (Human)

PRO ID PR:O60524
DAG View
PRO Name ribosome quality control complex subunit NEMF (human)
Definition A serologically defined colon cancer antigen 1 that is encoded in the genome of human.
Short Label hNEMF
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


O60524 (NEMF) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S6 Phosphorylation PhosphoSitePlus
T7 Phosphorylation PhosphoSitePlus   UniProt 23186163
Y30 Phosphorylation PhosphoSitePlus
K35 Ubiquitination PhosphoSitePlus
S89 Phosphorylation PhosphoSitePlus
Y117 Phosphorylation PhosphoSitePlus
Y127 Phosphorylation PhosphoSitePlus
Y129 Phosphorylation PhosphoSitePlus
T171 Phosphorylation PhosphoSitePlus
K179 Acetylation PhosphoSitePlus
K179 Ubiquitination PhosphoSitePlus
K184 Acetylation PhosphoSitePlus
K224 Ubiquitination PhosphoSitePlus
K245 Ubiquitination PhosphoSitePlus
C284 Methylation IEDB 31844290
K302 Ubiquitination PhosphoSitePlus
K311 Ubiquitination PhosphoSitePlus
K317 Ubiquitination PhosphoSitePlus
K345 Ubiquitination PhosphoSitePlus
K383 Ubiquitination PhosphoSitePlus
K397 Ubiquitination PhosphoSitePlus
K400 Ubiquitination PhosphoSitePlus
Y414 Phosphorylation PhosphoSitePlus
S417 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 21406692, 23186163, 18669648, ...24275569, 19690332, 20068231
Y470 Phosphorylation PhosphoSitePlus
Y477 Phosphorylation PhosphoSitePlus
Y482 Phosphorylation PhosphoSitePlus
K496 Ubiquitination PhosphoSitePlus
K520 Ubiquitination PhosphoSitePlus
Y629 Phosphorylation PhosphoSitePlus
T703 Phosphorylation phospho.ELM 17081983
S704 Phosphorylation phospho.ELM 17081983
S705 Phosphorylation phospho.ELM 17081983
S747 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 21406692, 17081983
S748 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 21406692, 17081983
S763 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648
T774 Phosphorylation PhosphoSitePlus
S785 Phosphorylation PhosphoSitePlus
S798 Phosphorylation PhosphoSitePlus
S805 Phosphorylation PhosphoSitePlus
S806 Phosphorylation PhosphoSitePlus
S808 Phosphorylation PhosphoSitePlus
K809 Ubiquitination PhosphoSitePlus
S831 Phosphorylation PhosphoSitePlus   UniProt 23186163, 20068231
S833 Phosphorylation PhosphoSitePlus
K875 Ubiquitination PhosphoSitePlus
K878 Ubiquitination PhosphoSitePlus
Y883 Phosphorylation PhosphoSitePlus
S900 Phosphorylation PhosphoSitePlus
S903 Phosphorylation PhosphoSitePlus
K916 Acetylation PhosphoSitePlus
K918 Acetylation PhosphoSitePlus
S936 Phosphorylation PhosphoSitePlus
T1016 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S417 Phosphorylation HPRD 19664994, 20058876, 18452278, ...19651622, 18669648, 19415658, 20068231
T516 Phosphorylation HPRD 17322306, 20068231
T682 Phosphorylation HPRD 17081983
S685 Phosphorylation HPRD 17081983
T687 Phosphorylation HPRD 17081983
S688 Phosphorylation HPRD 17081983
S692 Phosphorylation HPRD 17081983
T703 Phosphorylation HPRD 17081983
S704 Phosphorylation HPRD 17081983
S705 Phosphorylation HPRD 17081983
S747 Phosphorylation HPRD 19651622, 18669648, 17081983, ...18452278
S748 Phosphorylation HPRD 19651622, 18669648, 17081983, ...18452278
Y754 Phosphorylation HPRD 19651622
S763 Phosphorylation HPRD 18669648
S831 Phosphorylation HPRD 17322306, 19651622, 20068231
S833 Phosphorylation HPRD 17081983


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
Y117 C117 Biomuta DOID:5041 / esophageal cancer [ cosmic ]
K302 N302 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
K317 N317 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
T516 I516 Biomuta DOID:4159 / skin cancer [ cosmic ]
T703 M703 Biomuta DOID:1319 / brain cancer [ cosmic, icgc, tcga ]
S748 C748 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
S785 F785 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
S785 Y785 Biomuta DOID:10534 / stomach cancer [ cosmic ]
K809 T809 Biomuta DOID:3571 / liver cancer [ cosmic, icgc ]
S833 * Biomuta DOID:8618 / oral cavity cancer [ cosmic ]