iPTMnet Report for O60518 (RANBP6)


Protein Information

Cytoscape View


UniProt AC / UniProt ID O60518 / RNBP6_HUMAN
Protein Name Ran-binding protein 6
Gene Name Name: RANBP6
Organism Homo sapiens (Human)

PRO ID PR:O60518
DAG View
PRO Name Ran-binding protein 6 (human)
Definition A Ran-binding protein 6 that is encoded in the genome of human.
Short Label hRANBP6
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


O60518 (RANBP6) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
A2 Acetylation UniProt 19413330
T4 Phosphorylation PhosphoSitePlus
T12 Phosphorylation PhosphoSitePlus
S14 Phosphorylation PhosphoSitePlus
K16 Ubiquitination PhosphoSitePlus
S112 Phosphorylation PhosphoSitePlus
S247 Phosphorylation PhosphoSitePlus
S280 Phosphorylation PhosphoSitePlus
S614 Phosphorylation PhosphoSitePlus
K621 Ubiquitination PhosphoSitePlus
K625 Ubiquitination PhosphoSitePlus
Y630 Phosphorylation PhosphoSitePlus
T641 Phosphorylation PhosphoSitePlus
S660 Phosphorylation PhosphoSitePlus
Y707 Phosphorylation PhosphoSitePlus
T708 Phosphorylation PhosphoSitePlus
K720 Ubiquitination PhosphoSitePlus
K808 Ubiquitination PhosphoSitePlus
K814 Ubiquitination PhosphoSitePlus
R819 Methylation PhosphoSitePlus
K986 Ubiquitination PhosphoSitePlus
S1048 Phosphorylation PhosphoSitePlus
T1058 Phosphorylation HPRD 20068231
K1067 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T12 I12 Biomuta DOID:3571 / liver cancer [ cosmic ]
S14 L14 Biomuta DOID:363 / uterine cancer [ cosmic ]
S112 T112 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
S280 T280 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc, tcga ]
K621 N621 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
Y630 C630 Biomuta DOID:8618 / oral cavity cancer [ cosmic ] DOID:10534 / stomach cancer [ cosmic ]
T708 A708 Biomuta DOID:1319 / brain cancer [ cosmic ]
K808 T808 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
R819 K819 Biomuta DOID:4159 / skin cancer [ cosmic ]
K986 N986 Biomuta DOID:1324 / lung cancer [ cosmic ]