iPTMnet Report for O60507 (TPST1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID O60507 / TPST1_HUMAN
Protein Name Protein-tyrosine sulfotransferase 1
Gene Name Name: TPST1
Organism Homo sapiens (Human)

PRO ID PR:O60507
DAG View
PRO Name protein-tyrosine sulfotransferase 1 (human)
Definition A protein-tyrosine sulfotransferase 1 that is encoded in the genome of human.
Short Label hTPST1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


O60507 (TPST1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S46 O-Glycosylation GlyGen   PhosphoSitePlus 23584533
T47 O-Glycosylation GlyGen   PhosphoSitePlus 23584533, 25813380
T49 O-Glycosylation GlyGen   PhosphoSitePlus 23584533, 25813380
T50 O-Glycosylation GlyGen   PhosphoSitePlus 23584533, 25813380
T53 O-Glycosylation GlyGen   PhosphoSitePlus 23584533
N60 N-Glycosylation GlyGen   UniProt 16859706
Y65 Phosphorylation PhosphoSitePlus
S189 Phosphorylation PhosphoSitePlus
T199 O-Glycosylation GlyGen   PhosphoSitePlus 23584533
N262 N-Glycosylation GlyGen   UniProt 16859706
S279 Phosphorylation PhosphoSitePlus
S281 Phosphorylation PhosphoSitePlus
S286 O-Glycosylation GlyGen   PhosphoSitePlus 23584533, 25813380
S286 Phosphorylation HPRD   PhosphoSitePlus 19413330
T287 O-Glycosylation GlyGen   PhosphoSitePlus 23584533, 25813380


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T53 S53 Biomuta DOID:363 / uterine cancer [ icgc ]
S189 * Biomuta DOID:1324 / lung cancer [ cosmic ]
T287 A287 Biomuta DOID:1324 / lung cancer [ cosmic ]