iPTMnet Report for O60506 (SYNCRIP)


Protein Information

Cytoscape View


UniProt AC / UniProt ID O60506 / HNRPQ_HUMAN
Protein Name Heterogeneous nuclear ribonucleoprotein Q
Gene Name Name: SYNCRIP
Synonyms:HNRPQ,NSAP1;
Organism Homo sapiens (Human)

PRO ID PR:O60506
DAG View
PRO Name heterogeneous nuclear ribonucleoprotein Q (human)
Definition A heterogeneous nuclear ribonucleoprotein Q that is encoded in the genome of human.
Short Label hSYNCRIP
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


O60506 (SYNCRIP) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
A2 Acetylation UniProt 19413330
K42 Acetylation PhosphoSitePlus
Y47 Phosphorylation PhosphoSitePlus
S55 Phosphorylation PhosphoSitePlus
K66 Ubiquitination PhosphoSitePlus
K81 Acetylation PhosphoSitePlus
K81 Ubiquitination PhosphoSitePlus
K91 Ubiquitination PhosphoSitePlus
S92 Phosphorylation PhosphoSitePlus
K100 Acetylation PhosphoSitePlus
K100 Ubiquitination PhosphoSitePlus
K107 Ubiquitination PhosphoSitePlus
T110 Phosphorylation PhosphoSitePlus
K111 Ubiquitination PhosphoSitePlus
S115 Phosphorylation PhosphoSitePlus
S116 Phosphorylation PhosphoSitePlus
K117 Ubiquitination PhosphoSitePlus
K123 Acetylation PhosphoSitePlus
K123 Methylation PhosphoSitePlus
K123 Ubiquitination PhosphoSitePlus
K125 Methylation PhosphoSitePlus
Y133 Phosphorylation PhosphoSitePlus
T138 Phosphorylation PhosphoSitePlus
Y144 Phosphorylation PhosphoSitePlus
S159 Phosphorylation PhosphoSitePlus   UniProt 23186163
K168 Ubiquitination PhosphoSitePlus
K184 Ubiquitination PhosphoSitePlus
R192 Methylation PhosphoSitePlus
C211 Methylation IEDB 31844290
K213 Methylation PhosphoSitePlus
K221 Acetylation PhosphoSitePlus   UniProt 19608861
K221 Ubiquitination PhosphoSitePlus
Y223 Phosphorylation PhosphoSitePlus
C237 Methylation IEDB 31844290
S249 Phosphorylation PhosphoSitePlus
T255 Phosphorylation PhosphoSitePlus
K256 Ubiquitination PhosphoSitePlus
K265 Ubiquitination PhosphoSitePlus
Y276 Phosphorylation PhosphoSitePlus
K282 Acetylation PhosphoSitePlus
K282 Ubiquitination PhosphoSitePlus
K283 Acetylation PhosphoSitePlus
K283 Ubiquitination PhosphoSitePlus
K284 Ubiquitination PhosphoSitePlus
R286 Methylation PhosphoSitePlus
Y293 Phosphorylation PhosphoSitePlus
K297 Sumoylation PhosphoSitePlus
K297 Ubiquitination PhosphoSitePlus
K310 Ubiquitination PhosphoSitePlus
K312 Ubiquitination PhosphoSitePlus
K336 Ubiquitination PhosphoSitePlus
K338 Acetylation PhosphoSitePlus
K338 Ubiquitination PhosphoSitePlus
T348 Phosphorylation PhosphoSitePlus
K356 Ubiquitination PhosphoSitePlus
S359 Phosphorylation PhosphoSitePlus
K363 Acetylation PhosphoSitePlus   UniProt 19608861
K363 Methylation PhosphoSitePlus
K363 Ubiquitination PhosphoSitePlus
K371 Ubiquitination PhosphoSitePlus
Y373 Phosphorylation phospho.ELM   PhosphoSitePlus   Signor   UniProt 12601080
Y373 Phosphorylation P11362 (FGFR1) phospho.ELM   Signor 12601080
R381 Methylation PhosphoSitePlus
K386 Ubiquitination PhosphoSitePlus
K407 Ubiquitination PhosphoSitePlus
K412 Acetylation PhosphoSitePlus
K412 Ubiquitination PhosphoSitePlus
Y431 Phosphorylation PhosphoSitePlus
Y432 Phosphorylation PhosphoSitePlus
Y434 Phosphorylation PhosphoSitePlus
R444 Methylation PhosphoSitePlus   UniProt 23455924
R446 Methylation PhosphoSitePlus
R448 Methylation PhosphoSitePlus
Y472 Phosphorylation PhosphoSitePlus
Y474 Phosphorylation PhosphoSitePlus
R478 Methylation PhosphoSitePlus
Y485 Phosphorylation PhosphoSitePlus
Y488 Phosphorylation PhosphoSitePlus
R496 Methylation PhosphoSitePlus   UniProt 23455924
R498 Methylation PhosphoSitePlus
R501 Methylation PhosphoSitePlus
R504 Methylation PhosphoSitePlus
S509 Phosphorylation PhosphoSitePlus
R510 Methylation UniProt 23455924
R518 Methylation UniProt 23455924
R520 Methylation PhosphoSitePlus
S524 Phosphorylation PhosphoSitePlus
R526 Methylation PhosphoSitePlus   UniProt 23455924
S531 Phosphorylation PhosphoSitePlus
R533 Methylation PhosphoSitePlus
R536 Methylation UniProt 23455924
R539 Methylation UniProt 23455924
R565 Methylation PhosphoSitePlus
K566 Acetylation PhosphoSitePlus
K566 Ubiquitination PhosphoSitePlus
Y570 Phosphorylation PhosphoSitePlus
S575 Phosphorylation PhosphoSitePlus
K576 Acetylation PhosphoSitePlus
K576 Ubiquitination PhosphoSitePlus
T580 Phosphorylation PhosphoSitePlus
S587 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 17525332
S601 Phosphorylation PhosphoSitePlus
Y614 Phosphorylation PhosphoSitePlus
K623 Acetylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S249 Phosphorylation HPRD 20068231
S587 Phosphorylation HPRD 17525332


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S55 N55 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S55 I55 Biomuta DOID:363 / uterine cancer [ icgc ]
K107 R107 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
R192 C192 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
R192 H192 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
K256 N256 Biomuta DOID:4159 / skin cancer [ cosmic ] DOID:4606 / bile duct cancer [ cosmic ]
Y276 C276 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
K282 T282 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
K284 N284 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
R286 K286 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
K336 R336 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
T348 I348 Biomuta DOID:363 / uterine cancer [ icgc ]
K371 * Biomuta DOID:10283 / prostate cancer [ cosmic ]
R381 G381 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
R381 * Biomuta DOID:10534 / stomach cancer [ cosmic ]
R444 T444 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
R448 C448 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ] DOID:4159 / skin cancer [ cosmic ] DOID:10534 / stomach cancer [ cosmic ] DOID:9256 / colorectal cancer [ cosmic ]
R478 L478 Biomuta DOID:8618 / oral cavity cancer [ cosmic ]
R478 H478 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ] DOID:1324 / lung cancer [ cosmic, icgc ]
R478 C478 Biomuta DOID:4159 / skin cancer [ cosmic ] DOID:10534 / stomach cancer [ cosmic ]
R498 M498 Biomuta DOID:10283 / prostate cancer [ cosmic, icgc ]
R510 G510 Biomuta DOID:1324 / lung cancer [ cosmic ]
R518 P518 Biomuta DOID:263 / kidney cancer [ cosmic ]
R518 L518 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
R533 K533 Biomuta DOID:4159 / skin cancer [ cosmic ]
R533 T533 Biomuta DOID:4362 / cervical cancer [ cosmic, icgc ]
R536 * Biomuta DOID:9256 / colorectal cancer [ cosmic ] DOID:4606 / bile duct cancer [ cosmic ]
R565 C565 Biomuta DOID:9256 / colorectal cancer [ cosmic ] DOID:10534 / stomach cancer [ cosmic ]
R565 H565 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
S575 T575 Biomuta DOID:8618 / oral cavity cancer [ cosmic ] DOID:9256 / colorectal cancer [ cosmic ]