iPTMnet Report for O60504 (SORBS3)


Protein Information

Cytoscape View


UniProt AC / UniProt ID O60504 / VINEX_HUMAN
Protein Name Vinexin
Gene Name Name: SORBS3
Synonyms:SCAM1;
Organism Homo sapiens (Human)

PRO ID PR:O60504
DAG View
PRO Name vinexin (human)
Definition A vinexin that is encoded in the genome of human.
Short Label hSORBS3
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


O60504 (SORBS3) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
Q2 Acetylation UniProt 19369195, 22814378, 22223895, ...20068231
R6 Phosphorylation UniProt 19369195, 20068231
S13 Phosphorylation PhosphoSitePlus
T64 Phosphorylation PhosphoSitePlus
Y78 Phosphorylation neXtProt 16831423
Y78 Phosphorylation P00519 (ABL1) neXtProt 16831423
T80 Phosphorylation PhosphoSitePlus
K112 Acetylation PhosphoSitePlus
K116 Acetylation PhosphoSitePlus
S192 O-Glycosylation GlyGen 30379171, 36580660, 30059200
S217 Phosphorylation PhosphoSitePlus
T218 Phosphorylation PhosphoSitePlus
S283 Phosphorylation PhosphoSitePlus
S299 Phosphorylation PhosphoSitePlus
K301 Ubiquitination PhosphoSitePlus
S302 Phosphorylation PhosphoSitePlus
S303 Phosphorylation PhosphoSitePlus
S348 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 23186163, 17081983, 24275569
Y358 Phosphorylation PhosphoSitePlus
S361 Phosphorylation PhosphoSitePlus
T362 Phosphorylation PhosphoSitePlus
S366 Phosphorylation PhosphoSitePlus
S373 Phosphorylation PhosphoSitePlus
S395 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163, 20068231
K397 Ubiquitination PhosphoSitePlus
K403 Ubiquitination PhosphoSitePlus
Y408 Phosphorylation PhosphoSitePlus
K415 Ubiquitination PhosphoSitePlus
T497 Phosphorylation PhosphoSitePlus
T529 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S530 Phosphorylation phospho.ELM   PhosphoSitePlus   Signor   UniProt 23186163, 16964243, 18669648, ...24275569, 15184391, 19690332, 20068231, 17081983
S530 Phosphorylation P28482 (MAPK1) Signor 15184391
S539 Phosphorylation PhosphoSitePlus
S544 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163, 21406692
S545 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 21406692, 23186163, 17081983, ...18669648, 20068231
S547 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 24275569
S551 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 20068231, 24275569
T562 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648, 18847512
T562 Phosphorylation P24941 (CDK2) PhosphoSitePlus 18847512
S563 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 21406692, 23186163, 18220336, ...18847512, 18669648, 19690332, 20068231
S563 Phosphorylation P24941 (CDK2) PhosphoSitePlus 18847512
T585 Phosphorylation neXtProt   PhosphoSitePlus 22028470
T585 Phosphorylation P28482 (MAPK1) neXtProt 22028470
S593 Phosphorylation PhosphoSitePlus
R594 Methylation PhosphoSitePlus
S597 Phosphorylation PhosphoSitePlus
T604 Phosphorylation PhosphoSitePlus
S605 Phosphorylation PhosphoSitePlus
S606 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
T609 Phosphorylation PhosphoSitePlus
S610 Phosphorylation PhosphoSitePlus
T615 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
Site PTM Type PTM Enzyme Score Source PMID
S217 Phosphorylation HPRD 18691976
T218 Phosphorylation HPRD 18691976
S348 Phosphorylation HPRD 17081983, 20068231
S366 Phosphorylation HPRD 17081983
S373 Phosphorylation HPRD 19651622, 20068231
S395 Phosphorylation HPRD 18691976, 18669648, 19664994, ...20068231
T529 Phosphorylation HPRD 18691976, 17081983, 18767875, ...19664995, 18669648, 19415658, 20068231
S530 Phosphorylation HPRD 19413330, 18691976, 16964243, ...18767875, 15302935, 19664995, 18452278, 18669648, 19415658, 20068231
S544 Phosphorylation HPRD 17322306, 18767875, 18669648, ...20068231
S545 Phosphorylation HPRD 18691976, 18767875, 19651622, ...17322306, 18669648, 20068231
S547 Phosphorylation HPRD 18669648, 17081983
S551 Phosphorylation HPRD 17081983
T562 Phosphorylation HPRD 17322306
S563 Phosphorylation HPRD 17322306, 15302935
T585 Phosphorylation HPRD 20068231
T604 Phosphorylation HPRD 17081983, 20068231
S605 Phosphorylation HPRD 17081983, 20068231
S606 Phosphorylation HPRD 18669648, 17081983, 20068231
T609 Phosphorylation HPRD 20068231
S610 Phosphorylation HPRD 20068231
T615 Phosphorylation HPRD 18669648, 20068231
Site PTM Type PTM Enzyme Score Source PMID
S6 Phosphorylation HPRD 17081983, 20068231
S24 Phosphorylation HPRD 17081983
S31 Phosphorylation HPRD 19651622, 20068231
S53 Phosphorylation HPRD 18691976, 18669648, 19664994, ...20068231
T187 Phosphorylation HPRD 18691976, 17081983, 18767875, ...19664995, 18669648, 19415658, 20068231
S188 Phosphorylation HPRD   neXtProt   PhosphoSitePlus 19413330, 18691976, 16964243, ...18767875, 15302935, 19664995, 18452278, 18669648, 15184391, 19415658, 20068231
S188 Phosphorylation P28482 (MAPK1) neXtProt   PhosphoSitePlus 15184391
S202 Phosphorylation HPRD 17322306, 18767875, 18669648, ...20068231
S203 Phosphorylation HPRD   PhosphoSitePlus 17322306, 18691976, 18767875, ...19651622, 18669648, 20068231
S205 Phosphorylation HPRD 18669648
S209 Phosphorylation HPRD 17081983
S221 Phosphorylation HPRD   PhosphoSitePlus 15302935
T243 Phosphorylation HPRD 20068231
T262 Phosphorylation HPRD 17081983, 20068231
S263 Phosphorylation HPRD 17081983, 20068231
S264 Phosphorylation HPRD 18669648, 17081983, 20068231
T267 Phosphorylation HPRD 20068231
S268 Phosphorylation HPRD 20068231
T273 Phosphorylation HPRD 18669648, 20068231


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S205 L205 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
S209 N209 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S263 F263 Biomuta DOID:4159 / skin cancer [ cosmic ]
S299 P299 Biomuta DOID:10534 / stomach cancer [ cosmic ]
K301 R301 Biomuta DOID:363 / uterine cancer [ cosmic ]
S361 L361 Biomuta DOID:4159 / skin cancer [ cosmic ]
S547 L547 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
S551 N551 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S605 F605 Biomuta DOID:4159 / skin cancer [ cosmic ]