iPTMnet Report for O60502 (OGA)


Protein Information

Cytoscape View


UniProt AC / UniProt ID O60502 / OGA_HUMAN
Protein Name Protein O-GlcNAcase
Gene Name Name: OGA
Synonyms:HEXC,KIAA0679,MEA5,MGEA5;
Organism Homo sapiens (Human)

PRO ID PR:O60502
DAG View
PRO Name protein O-GlcNAcase (human)
Definition A protein O-GlcNAcase that is encoded in the genome of human.
Short Label hOGA
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


O60502 (OGA) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S6 Phosphorylation PhosphoSitePlus
K87 Ubiquitination PhosphoSitePlus
K98 Ubiquitination PhosphoSitePlus
K157 Ubiquitination PhosphoSitePlus
K240 Ubiquitination PhosphoSitePlus
K253 Ubiquitination PhosphoSitePlus
K257 Ubiquitination PhosphoSitePlus
S268 Phosphorylation PhosphoSitePlus
K269 Ubiquitination PhosphoSitePlus
K272 Ubiquitination PhosphoSitePlus
K289 Ubiquitination PhosphoSitePlus
K297 Ubiquitination PhosphoSitePlus
K358 Sumoylation PhosphoSitePlus
S364 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 21406692, 23186163, 15302935, ...18669648, 19690332, 20068231
T370 Phosphorylation PhosphoSitePlus
S398 O-Glycosylation GlyGen 33214551, 28510447, 35138101, ...30379171, 34725712, 26853435, 34065225, 35254053, 24995865, 34019948, 16434389, 29485866, 32119511, 29351928, 30059200
S399 O-Glycosylation GlyGen 33214551, 28510447, 35138101, ...30379171, 34725712, 26853435, 34065225, 35254053, 24995865, 34019948, 16434389, 29485866, 32119511, 29351928, 30059200
S405 O-Glycosylation GlyGen   PhosphoSitePlus 33214551, 28510447, 35138101, ...25813380, 34725712, 26853435, 34065225, 35254053, 24995865, 23584533, 34019948, 16434389, 30379171, 29485866, 32119511, 29351928, 30059200
S410 O-Glycosylation GlyGen 33214551, 28510447, 35138101, ...30379171, 34725712, 26853435, 34065225, 35254053, 24995865, 34019948, 16434389, 29485866, 32119511, 29351928, 30059200
T415 O-Glycosylation GlyGen 33214551, 28510447, 35138101, ...30379171, 34725712, 26853435, 34065225, 35254053, 24995865, 34019948, 16434389, 29485866, 32119511, 29351928, 30059200
S505 Phosphorylation PhosphoSitePlus
S509 Phosphorylation PhosphoSitePlus
S511 Phosphorylation PhosphoSitePlus
S522 Phosphorylation PhosphoSitePlus
K597 Ubiquitination PhosphoSitePlus
K599 Ubiquitination PhosphoSitePlus
K613 Ubiquitination PhosphoSitePlus
T709 Phosphorylation P28482 (MAPK1) neXtProt   phospho.ELM   PhosphoSitePlus 18669648, 22028470
S712 Phosphorylation PhosphoSitePlus
K723 Ubiquitination PhosphoSitePlus
K730 Ubiquitination PhosphoSitePlus
K794 Ubiquitination PhosphoSitePlus
K807 Ubiquitination PhosphoSitePlus
K850 Ubiquitination PhosphoSitePlus
K858 Ubiquitination PhosphoSitePlus
K869 Ubiquitination PhosphoSitePlus
K885 Ubiquitination PhosphoSitePlus
K893 Ubiquitination PhosphoSitePlus
C896 S-Nitrosylation dbSNO 19483679
K901 Ubiquitination PhosphoSitePlus
K907 Ubiquitination PhosphoSitePlus
S915 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S364 Phosphorylation HPRD 19413330, 19664994, 15302935, ...19651622, 18669648, 18707149, 20166139, 15345747, 19415658, 20068231
T709 Phosphorylation HPRD 18669648
S859 Phosphorylation HPRD 20068231
S867 Phosphorylation HPRD 20068231
S873 Phosphorylation HPRD 20068231


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K87 I87 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S398 N398 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
T415 I415 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S522 G522 Biomuta DOID:4159 / skin cancer [ cosmic ] DOID:9256 / colorectal cancer [ cosmic, icgc ]
S712 F712 Biomuta DOID:4159 / skin cancer [ cosmic ]
C896 Y896 Biomuta DOID:5041 / esophageal cancer [ cosmic ]