iPTMnet Report for O60494 (CUBN)


Protein Information

Cytoscape View


UniProt AC / UniProt ID O60494 / CUBN_HUMAN
Protein Name Cubilin precursor
Gene Name Name: CUBN
Synonyms:IFCR;
Organism Homo sapiens (Human)

PRO ID PR:O60494
DAG View
PRO Name cubilin (human)
Definition A cubilin that is encoded in the genome of human.
Short Label hCUBN
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


O60494 (CUBN) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S107 Phosphorylation PhosphoSitePlus
S108 Phosphorylation PhosphoSitePlus
Y111 Phosphorylation PhosphoSitePlus
S115 Phosphorylation PhosphoSitePlus
S669 Phosphorylation PhosphoSitePlus
S688 O-Glycosylation GlyGen 30459171
N984 N-Glycosylation GlyGen   UniProt 20237569
T1079 Phosphorylation PhosphoSitePlus
N1092 N-Glycosylation GlyGen   UniProt 20237569
N1168 N-Glycosylation GlyGen   UniProt 20237569
N1217 N-Glycosylation GlyGen   UniProt 20237569
N1285 N-Glycosylation GlyGen   UniProt 20237569
N1307 N-Glycosylation GlyGen   UniProt 20237569
N1319 N-Glycosylation GlyGen   UniProt 20237569
N1332 N-Glycosylation GlyGen   UniProt 20237569
Y1350 Phosphorylation PhosphoSitePlus
R1469 Methylation PhosphoSitePlus
K1909 Methylation PhosphoSitePlus
T1972 O-Glycosylation GlyGen 30459171
S2075 Phosphorylation PhosphoSitePlus
S2077 Phosphorylation PhosphoSitePlus
S2078 Phosphorylation PhosphoSitePlus
N2085 N-Glycosylation GlyGen 26791533
Y2108 Phosphorylation PhosphoSitePlus
T2483 Phosphorylation PhosphoSitePlus
N2531 N-Glycosylation GlyGen 29671580
S2904 O-Glycosylation GlyGen 30459171
S3115 Phosphorylation PhosphoSitePlus
T3139 Phosphorylation PhosphoSitePlus
Y3486 Phosphorylation PhosphoSitePlus
S3491 Phosphorylation PhosphoSitePlus
S3493 Phosphorylation PhosphoSitePlus
T3495 Phosphorylation PhosphoSitePlus
Y3500 Phosphorylation PhosphoSitePlus
S3509 Phosphorylation PhosphoSitePlus
Y3516 Phosphorylation PhosphoSitePlus
S3591 O-Glycosylation GlyGen 30459171
Site PTM Type PTM Enzyme Score Source PMID
N2085 N-Glycosylation PRO 26791533
N2531 N-Glycosylation PRO 29671580


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S108 I108 Biomuta DOID:263 / kidney cancer [ cosmic, icgc ]
N1092 K1092 Biomuta DOID:3571 / liver cancer [ cosmic ]
N1307 Y1307 Biomuta DOID:1319 / brain cancer [ cosmic ]
N1319 D1319 Biomuta DOID:1319 / brain cancer [ cosmic, icgc ]
N1332 H1332 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
N1332 S1332 Biomuta DOID:1612 / breast cancer [ cosmic ]
S2078 N2078 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S2078 R2078 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
Y3486 C3486 Biomuta DOID:5041 / esophageal cancer [ cosmic, icgc ]
S3491 I3491 Biomuta DOID:1324 / lung cancer [ cosmic ]
S3509 C3509 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S3591 I3591 Biomuta DOID:9256 / colorectal cancer [ cosmic ]