iPTMnet Report for O60486 (PLXNC1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID O60486 / PLXC1_HUMAN
Protein Name Plexin-C1 precursor
Gene Name Name: PLXNC1
Synonyms:VESPR;
Organism Homo sapiens (Human)

PRO ID PR:O60486
DAG View
PRO Name plexin-C1 (human)
Definition A plexin-C1 that is encoded in the genome of human.
Short Label hPLXNC1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


O60486 (PLXNC1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
N86 N-Glycosylation GlyGen   UniProt 20727575, 24190977
N141 N-Glycosylation GlyGen   UniProt 20727575, 24190977
N149 N-Glycosylation GlyGen   UniProt 20727575
N241 N-Glycosylation GlyGen   UniProt 20727575
N252 N-Glycosylation GlyGen   UniProt 20727575
N386 N-Glycosylation GlyGen   UniProt 20727575
N407 N-Glycosylation GlyGen   UniProt 23345538, 20727575, 24190977
N411 N-Glycosylation GlyGen 24190977
Y438 Phosphorylation PhosphoSitePlus
Y440 Phosphorylation PhosphoSitePlus
T519 Phosphorylation PhosphoSitePlus
N548 N-Glycosylation GlyGen 23345538
T562 Phosphorylation PhosphoSitePlus
T565 Phosphorylation PhosphoSitePlus
Y566 Phosphorylation PhosphoSitePlus
T683 Phosphorylation PhosphoSitePlus
N686 N-Glycosylation GlyGen 24190977
N692 N-Glycosylation GlyGen 24190977
N715 N-Glycosylation GlyGen 24190977
N771 N-Glycosylation GlyGen 23345538
N871 N-Glycosylation GlyGen 29741879, 23345538, 24190977
K913 Ubiquitination PhosphoSitePlus
N920 N-Glycosylation GlyGen 24190977
S978 Phosphorylation PhosphoSitePlus
S986 Phosphorylation PhosphoSitePlus
Y1101 Phosphorylation PhosphoSitePlus
T1110 Phosphorylation PhosphoSitePlus
R1127 Methylation PhosphoSitePlus
R1128 Methylation PhosphoSitePlus
S1131 Phosphorylation PhosphoSitePlus
S1146 Phosphorylation PhosphoSitePlus
T1299 Phosphorylation HPRD   PhosphoSitePlus 18452278
N1308 N-Glycosylation GlyGen 23345538
Y1350 Phosphorylation PhosphoSitePlus
T1466 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 17081983
Y1527 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
N407 N-Glycosylation PRO 23345538
N548 N-Glycosylation PRO 23345538
N771 N-Glycosylation PRO 23345538
N871 N-Glycosylation PRO 23345538
N1308 N-Glycosylation PRO 23345538


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
N149 K149 Biomuta DOID:5041 / esophageal cancer [ cosmic ]
T683 M683 Biomuta DOID:1793 / pancreatic cancer [ cosmic ] DOID:9256 / colorectal cancer [ cosmic ]
R1128 H1128 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ] DOID:10534 / stomach cancer [ cosmic, icgc ]
R1128 C1128 Biomuta DOID:9256 / colorectal cancer [ cosmic ] DOID:10534 / stomach cancer [ cosmic ]
S1131 P1131 Biomuta DOID:3571 / liver cancer [ cosmic ]
N1308 T1308 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
Y1527 N1527 Biomuta DOID:3571 / liver cancer [ cosmic ]
Y1527 * Biomuta DOID:363 / uterine cancer [ cosmic ]