Protein Information

Cytoscape View


UniProt AC / UniProt ID O60447 / EVI5_HUMAN
Protein Name Ecotropic viral integration site 5 protein homolog
Gene Name Name: EVI5
Synonyms:NB4S;
Organism Homo sapiens (Human)

PRO ID PR:O60447
DAG View
PRO Name ecotropic viral integration site 5 protein homolog (human)
Definition An ecotropic viral integration site 5 protein that is encoded in the genome of human.
Short Label hEVI5
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


O60447 (EVI5) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S14 Phosphorylation PhosphoSitePlus
S32 Phosphorylation PhosphoSitePlus
T37 Phosphorylation PhosphoSitePlus
S43 Phosphorylation PhosphoSitePlus
S47 Phosphorylation PhosphoSitePlus
S102 Phosphorylation PhosphoSitePlus   UniProt 23186163
S105 Phosphorylation PhosphoSitePlus
S113 Phosphorylation PhosphoSitePlus
S115 Phosphorylation PhosphoSitePlus
S116 Phosphorylation PhosphoSitePlus
S128 Phosphorylation PhosphoSitePlus
S477 Phosphorylation phospho.ELM   PhosphoSitePlus 16565220
K493 Ubiquitination PhosphoSitePlus
S497 Phosphorylation PhosphoSitePlus   UniProt 24275569
T546 Phosphorylation PhosphoSitePlus
S687 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S689 Phosphorylation PhosphoSitePlus   UniProt 23186163
S776 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648
S778 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
T780 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S783 Phosphorylation phospho.ELM 18669648
S805 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S477 Phosphorylation HPRD 16565220
S687 Phosphorylation HPRD 18669648
S776 Phosphorylation HPRD 19413330, 18669648, 20068231
S778 Phosphorylation HPRD 19413330, 18669648, 20068231
T780 Phosphorylation HPRD 18669648
S783 Phosphorylation HPRD 18669648


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S102 C102 Biomuta DOID:1324 / lung cancer [ cosmic ]
S115 F115 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc, tcga ]
S115 Y115 Biomuta DOID:363 / uterine cancer [ tcga ]
S783 N783 Biomuta DOID:363 / uterine cancer [ tcga ]
S805 L805 Biomuta DOID:363 / uterine cancer [ tcga ] DOID:10534 / stomach cancer [ cosmic, icgc, tcga ]