iPTMnet Report for O60423 (ATP8B3)


Protein Information

Cytoscape View


UniProt AC / UniProt ID O60423 / AT8B3_HUMAN
Protein Name Phospholipid-transporting ATPase IK
Gene Name Name: ATP8B3
Synonyms:ATP1K,FOS37502_2;
Organism Homo sapiens (Human)

PRO ID PR:O60423
DAG View
PRO Name phospholipid-transporting ATPase IK (human)
Definition A phospholipid-transporting ATPase IK that is encoded in the genome of human.
Short Label hATP8B3
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


O60423 (ATP8B3) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T8 Phosphorylation PhosphoSitePlus
K108 Ubiquitination PhosphoSitePlus
K123 Ubiquitination PhosphoSitePlus
K225 Ubiquitination PhosphoSitePlus
K231 Ubiquitination PhosphoSitePlus
K296 Ubiquitination PhosphoSitePlus
S299 Phosphorylation PhosphoSitePlus
K326 Ubiquitination PhosphoSitePlus
Y348 Phosphorylation PhosphoSitePlus
T372 Phosphorylation PhosphoSitePlus
K496 Ubiquitination PhosphoSitePlus
K509 Ubiquitination PhosphoSitePlus
S579 Phosphorylation phospho.ELM   PhosphoSitePlus 17081983
S645 Phosphorylation PhosphoSitePlus
S755 Phosphorylation PhosphoSitePlus
T763 Phosphorylation PhosphoSitePlus
T769 Phosphorylation PhosphoSitePlus
S781 Phosphorylation PhosphoSitePlus
S832 Phosphorylation PhosphoSitePlus
S867 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
T372 Phosphorylation HPRD 19664994


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T8 N8 Biomuta DOID:3571 / liver cancer [ cosmic ]
K225 N225 Biomuta DOID:8618 / oral cavity cancer [ cosmic ]
S299 F299 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
K326 Q326 Biomuta DOID:363 / uterine cancer [ icgc ]
Y348 C348 Biomuta DOID:3571 / liver cancer [ cosmic ]
T372 S372 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
K509 M509 Biomuta DOID:3571 / liver cancer [ cosmic ]
S755 I755 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
T769 M769 Biomuta DOID:10283 / prostate cancer [ cosmic ]
S781 * Biomuta DOID:1324 / lung cancer [ cosmic ]